(Cp* η5-C5Me5) reacted with an excess of CH2CHX (X COMe, SO2Ph, COOMe, CN) in the presence of NEt3(4 equiv) in MeCN to afford the diiridium complexes [Cp*Ir(μ-SCH2CH2X)3IrCp*]Cl4, which contain three bridging thiolato ligands derived from the Michael addition of the μ-...
The following sections are included:Addition of Neutral NucleophilesAddition of Charged NucleophilesNucleophilic substitutionReferences Addition of Neutral Nucleophiles Addition of Charged Nucleophiles Nucleophilic substitution ReferencesThe Chemistry Of Fullerenes...
In the presence ofstrongnucleophiles, benzene can do a Nucleophilic Aromatic Substitution, also calledSNAR. Unlike EAS, where addition is initiated by the presence of a strongelectrophile, addition-elimination can also be initiated by a strongnucleophilein the presence of agood aryl...
Interactive 3D animation of SN2' (prime) substitution at an allylic centre for students studying University chemistry
Learn about nucleophilic substitution. Explore two types of nucleophilic substitution reactions: study SN1 and SN2 reaction mechanisms and...
In this lesson we'll be looking at the mechanism of nucleophilic aromatic substitution reactions including addition-elimination and the formation of the Meisenheimer complex as well as elimination-addition reactions. What Are Nucleophilic Aromatic Substitution Reactions?
ChemInform Abstract: The Rapid Steps in Nucleophilic Vinylic “Addition-Elimination” Substitution. Recent Developments 1992. The rapid steps in nucleophilic vinylic ``addition-elimination'' substitution. Recent developments. Acc. Chem. Res. 25:474-479... ...
Reactions of 3-R-5- nitropyridines with nucleophiles: Nucleophilic substitution vs conjugate addition. Tetrahedron 2019, 75, 130659. [CrossRef] 13. Frank, R.; Christoph, T.; Lesch, B.; Lee, J. Substituted heterocyclic aza derivatives. WO Patent 2013013817, 31 January 2013. 14. Van der ...
21. Aldehydes and Ketones: Nucleophilic Addition Topic summary Created using AI Thenucleophilic additionof solvents to carbonyl compounds, such as ketones and aldehydes, showcases their high reactivity due to the carbonyl carbon's strong partial positive charge. Reactions...
The observed regioselectivity of nucleophilic addition to substituted cyclohexynes is rationalized from calculated LUMO populations, which are governed by the bond angles at the acetylenic carbons: The less deformed carbon has a higher LUMO population and is preferentially attacked by the nucleophile....