This paper describes the major nucleic acid and protein sequence database - GENBANK, EMBL, SWISS-PROT, PIR and HGML. Access to the database in their various formats is described.doi:10.1300/J122v11n01_09KehoeKathleenScience & Technology Libraries...
Compartmentalization of phase-separated microdroplets is a key challenge in emulating native cells. Here, the authors report the assembly of compartmentalized, phase-separated cyanuric acid/polyadenine coacervate microdroplets, and the switchable light-stimulated and catalytic reconfiguration of their compartment...
In one aspect, the application provides a systematic method of creating a database of related protein or nucleic acid sequences with annotations of the potential disease associations of the sequences; and a method for testing the potential disease associations by means of a biological assay and ...
Nucleic acids are macromolecule composed of nucleotides, which aid in the storage of genetic material and protein production in the cell. Two different nucleic acid sequences are usually present in cells such as deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) based on the sugar component pr...
Nanostructures built from biomolecules such as proteins, DNA and RNA are attracting attention in many areas of biological and materials sciences. Such nanoscale engineering was pioneered with proteins, yet the use of DNA is rapidly gaining traction. What
50 kDa protein 2.7 kb DNA → 100 kDa protein average MW of an amino acid ≈ 110 daltons Dalton (Da) is an alternate name for the atomic mass unit, and kilodalton (kDa) is 1,000 daltons. Thus a protein with a mass of 64 kDa has a molecular weight of 64,000 grams per mole ...
Nucleic acid Nucleic acids (NA) are powerful gene regulators that forming fundamental molecules of life, have been delivered against a single gene target and shown promising consequences in tumor therapy[26–28]. Typically, NA-based therapy combined with nanotechnology can be categorized into three ...
protein–nucleic acid interaction can be increased through protein oligomerization or multi-protein complex formation (e.g., GCN4, glucocorticoid receptor, transcription initiation complexes, mRNA splicing complexes, RISC, etc....
Explore our “Getting Started” and Troubleshooting sections for solutions to the top inquiries and common problems related to your protein-nucleic acid interaction experiments. Browse through our “Guides and Tools” section to access a comprehensive p...
Protein–RNA and protein–DNA complexes play critical roles in biology. Despite considerable recent advances in protein structure prediction, the prediction of the structures of protein–nucleic acid complexes without homology to known complexes is a lar