Nuclei from nerve, astrocytic and other glial cells were purified in hypertonic sucrose and their protein synthesis investigated under carefully optimized conditions of incubation. The incorporation of labelled amino acid into the proteins of brain nuclei and of liver nuclei treated in the same way, ...
Nuclei from nerve, astrocytic and other glial cells were purified in hypertonic sucrose and their protein synthesis investigated under carefully optimized conditions of incubation. The incorporation of labelled amino acid into the proteins of brain nuclei and of liver nuclei treated in the same way, ...
When the nuclei of mammalian somatic cells are transplanted to amphibian oocytes in the first meiotic prophase, they are rapidly induced to begin transcribing several pluripotency genes, including Sox2 and Oct4. The more differentiated the donor cells of the nuclei, the longer it takes for the plu...
S. P. R. Rose, Preparation of enriched fractions from cerebral cortex containing isolated, metabolically active neuronal and glial cells, Biochem. J. 102: 33–43 (1967). PubMed CAS PubMed Central Google Scholar M. Satake and S. Abe, Preparation and characterization of nerve cell perikaryon...
Finally, we also see evidence of a similar disease゛ssociated expression signature in oligodendroglial cells, suggesting potentially an interaction between the disease associated microglia populations and oligodendrocytes in diseased patients that warrants further functional investigation.doi:10.1002/alz.046122...
Striking reduction in neurons and glial cells in anterior thalamic nuclei of older patients with Down syndrome. Neurobiol. Aging 75, 54–61 (2019). Article CAS PubMed PubMed Central Google Scholar O’Mara, S. M. & Aggleton, J. P. Space and memory (far) beyond the hippocampus: many ...
we and others have reported alterations in inflammatory signaling5,9, along with pathways involved in neurodegeneration2,6,7, oxidative stress10, and DNA damage11in the brains of individuals with OUD. Glial cells are likely major contributors to inflammation in the brain associated with chronic opio...
Neuroglial interaction is very important for functioning and survival of nerve and glial cells. In the present work. we studied the influence of the intense neuronal activity on survival of the isolated crayfish stretch receptor neuron and surrounding glial cells subjected to photodynamic treatment, ...
Thus, cell number estimates always vary and the range of such variation needs to be known. Automatic detection of neurons and glial cells would be an important step in a large number of neuroanatomical studies, not only to estimate the number of different cell types, but also to obtain three...
We present a nuclei isolation protocol for genomic and epigenomic interrogation of multiple cell type populations in the human and rodent brain. The nuclei isolation protocol allows cell type-specific profiling of neurons, microglia, oligodendrocytes, and astrocytes, being compatible with fresh and frozen...