1.11 NFI A/B/X The Nuclear Factor I (Nfi) genes are a family of transcription factors recently described as initiators of gliogenesis and late-stage neuron generation in the mouse spinal cord and retina [60,61]. Comparative analyses of different CNS regions indicate that Nfia/b/x are gene...
nuclear factor﹌B transcription factorproinflammatory cytokinesRNA virustranscriptional regulationNuclear factor (NF)-κB activating signals, which are discussed in this chapter, induce phosphorylation of I κB proteins, leading to their ubiquitination and proteasome-mediated degradation. Nuclear translocation of...
Permeabilization conditions required for staining transcription factors using True-Nuclear™ (or Foxp3 Fix/Perm and Nuclear Factor Fixation and Permeabilization Buffer Sets) is much harsher than those generally recommended for staining cytokines (i.e.- cells become more porous). Therefore, cytokin...
网络释义 1. 细胞核转录因子 ...发一系列的protein kinase,以造成更多细胞核转录因子(nuclear transcription factors)的磷酸化,促使细胞成长分裂。www.tma.tw|基于1 个网页 例句 释义: 全部,细胞核转录因子 更多例句筛选 1. TH receptors are nuclear transcription factors that, through TH-binding, activate or ...
NRF2 is the main redox-dependent transcription factor driving HPC fate To identify the role of redox-modulated transcription factors in HPCs, we compared progenitors with differentiated cells. For the purpose of characterizing the main redox-dependent mechanisms that initiate HPCs differentiation, we st...
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HNF-1A is part of a regulatory circuit involving other transcription factors like the pancreatic duodenal homeobox-1 (PDX-1), the hepatocyte nuclear factor-4 alpha (HNF-4A) and-1 beta (HNF-1B), which are important for normal glucose-induced insulin secretion1,2. In mice, loss ofHnf1afunct...
NF-κB is an important transcription factor that participates in different cellular pathways involving apoptosis, oxidative stress, and inflammation[15]. In astrocytes, NF-κB signaling contributes to pro-inflammatory responses following injury[16]. Moreover, NF-κB acts as a signaling hub that ...
However, little is known about whether and how NONO, as a transcription factor, promotes malignant progression or metastasis of TNBC. Pyruvate kinase (PK), a rate-limiting enzyme in glycolysis, catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP...
The nuclear corepressors NCOR1 and NCOR2 interact with transcription factors involved in B cell development and potentially link these factors to alterations in chromatin structure and gene expression. Herein, we demonstrate that Ncor1/2 deletion limits B cell differentiation via impaired recombination,...