The envelope is an anchorage structure for the nuclear architecture. A number of proteins are associated with the NE. They can be categorized into three groups according to their position in the NE (Fig.1). The first group is the trans-nuclear membrane proteins in the nuclear pore complex (...
thenuclear envelopemaintains aresting potential, osmotic forces manifest themselves, and ion-selective channels exist in the envelope. The protein-within-a-protein is a common motif. The chapter also explains that the eight-plus-one structure of the nuclear pore complex is reminiscent of a chaperone...
Nuclear pore complexes (NPCs) are indispensable for cell function and are at the center of several human diseases. NPCs provide access to the nucleus and regulate the transport of proteins and RNA across the nuclear envelope. They are aqueous channels generated from a complex network of evolutionar...
Although transport is the primary function of the NPC, recent research has revealed that the NPC plays an important part in cellular functions taking place on either side of the nuclear envelope. The nuclear basket is a distinct structure extending from the NPC into the nucleus. It is thought ...
Lipid saturation controls nuclear envelope function. Nat. Cell Biol. 25, 1290–1302 (2023). Article CAS PubMed PubMed Central Google Scholar Jarnik, M. & Aebi, U. Toward a more complete 3-D structure of the nuclear pore complex. J. Struct. Biol. 107, 291–308 (1991). Article CAS ...
One additional and, without doubt, highly impressive aspect is the recently identified key function of selected nuclear envelope components in driving meiotic chromosome dynamics, which in turn is essential for accurate recombination and segregation of the homologous chromosomes. Here, we summarize the ...
The organization and function of the nuclear envelope (NE) involves hundreds of nuclear membrane proteins and myriad protein–protein interactions, most of which are still uncharacterized. Many NE proteins interact stably or dynamically with the nuclear lamina or chromosomes. This can make them difficul...
Patch-clamp, fluorescence microscopy and high-resolution EM have yielded new data which question current concepts of ion transport across the nuclear envelope. The current challenge is to prove that NICs play an important role in nuclear function either through their identity with NPCs or parts there...
(INM). These nuclear envelope transmembrane proteins (NETs) play important roles in cellular function and participate in transcription, epigenetics, splicing, DNA replication, genome architecture, nuclear structure, nuclear stability, nuclear organization, and nuclear positioning. These vital functions are ...
envelope of the package's capabilities. The unique minesweeper that uses an image for the board was created by Israel.@jason990420surprised many when he published the first card game using PySimpleGUI that you see pictured above as well as the first minesweeper game made with PySimpleGUI.@Chr...