Elevation of ANA titer is the most sensitive of the ACR criteria. There are different methods for detection of ANA. Indirect immunofluorescence (ANA-IFA) and enzyme immunoassay (ANA-EIA) are commonly used methods. The sensitivity of ANA-IFA using HEp-2 cell substrate is 90–100% in systemic...
NuclearAntibody(ANA) E.Hightiters(>1:320)ishighlysuggestiveofan autoimmunedisease F.Lowornegativeresultdoesnotruleout autoimmunedisease G.Manypatientswithdifferentkindsof autoimmunediseaseswillhavegenericANA’s H.SpecifictypesofANA’swillhelptoidentifya specificautoimmunediseases: 3 Anti-NuclearAntibody(ANA) ...
ICARE improves antinuclear antibody detection by overcoming the barriers preventing accreditation 2016, Clinica Chimica Acta Citation Excerpt : In addition, our results can be compared with those of enzyme immunoassays (EIA) for detection of ANA. Reported intra- and inter-assay CVs for EIA are under...
摘要: In this study, our objective is to compare the efficacy of the IFA and EIA methods in the detection of anti-nuclear antibodies (ANA) and anti-double stranded DNA (Anti-dsDNA) in patients with prediagnosed as systemic lupus erythematosus (SLE). All serum samples (n...
THE CLINICAL-SIGNIFICANCE OF ANTICYTOPLASMIC ANTIBODIES FOUND ON FLUORESCENT ANTI-NUCLEAR ANTIBODY TESTING FRIOU G. TESSER,JRP,ROTHBERGER,... - 《Journal of Rheumatology》 被引量: 2发表: 1983年 Antibodies to cytomegalovirus-induced pre-early nuclear antigen in the anticomplement-immunofluorescent test...
To investigate whether this could be autoimmune mediated we analyzed for ANA in the plasma of 25 MSA, 25 PD, and 17 DLB patients, along with 25 healthy controls, using the ANA HEp-2 indirect immunofluorescence antibody assay (ANA HEp-2 IFA). Contrary to initial expectations, results showed ...