Why NTRK fusion testing is becoming important. Different methods of NTRK fusion detection, including their pros and cons based on real data from lung cancer testing. How developments in precision oncology are changing not only cancer care, but also the way we should approach biomarker testing in...
The authors proposed a testing algorithm for oncogenic neurotrophic tropomyosin receptor kinase gene fusion screening and diagnosis for the Brazilian health system. This review aims to discuss the latest literature evidence and international consensus on neurotrophic tropomyosin receptor ...
Mark A. Socinski, MD provides insight on biomarker testing to identify patients with NTRK gene fusion-positive non–small cell lung cancer. Read More FDA Clears Phase 1/2 Study of ABT-101 in Non–Small Cell Lung Cancer Jordyn Sava
NTRK Testing Quick Reference Guide (Updated June 2021) NTRK gene fusions can drive unregulated cell growth and proliferation in a range of cancer types. Molecular profiling has unveiled the complexity of TRK fusion-positive cancers. Next-generation sequencing provides the most comprehensive view ...
Learn about biomarker testing, to inform precision medicine including NTRK testing at cancer diagnosis, such as lung cancer and thyroid cancer.
5.Westphalen CB, Krebs MG, Le Tourneau C, et al. Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population. NPJ Precis Oncol. 2021;5(1):69. 6.Penault-Llorca F, Rudzinski ER, Sepulveda AR. Testing algorithm for identification of patients with TRK fusion ...
Learn about VITRAKVI® (larotrectinib), a treatment for NTRK gene fusion positive solid tumors in adult and pediatric patients. See safety and full prescribing Info.
7. European Society for Medical Oncology (ESMO). Importance of testing cancers for NTRK gene fusions. Available at https://oncologypro.esmo.org/oncology-in-practice/anti-cancer-agents-and-biological-therapy/targeting-ntrk-gene-fusions/importance-of-testing-cancers-for-ntrk-gene-fusions. Accessed ...
NTRK GENE FUSIONS SARCOMA SKIN CANCERSSKIN CANCERS THYROID CANCERS A 67-Year-Old Man With NTRK Fusion-Positive Metastatic Lung Cancer: Episode3 ByLuis E. Raez, MD Video Luis Raez, MD:Usually, when we find a genetic alteration that can be targeted, that is the preferred modality for treatme...
Currently, there is limited experience with NTRK gene fusion testing in Belgium. The lack of an external quality assessment (EQA) for the pan-TRK IHC staining prompted us to organise a pan-TRK IHC ring trial. The key aim was to evaluate the reproducibility of TRK staining across different ...