The core conserved strands that are shared by all ASCE division NTPases are numbered 1-5, and X indicates additional strands that are observed only in certain NTPases. Full size image Most of the NTPases of the KAP family have a variable α-helical insert amino-terminal to the Walker B ...
The Walker A motif was excluded from the alignments for the construction of these PSSMs to avoid the generic attraction of the searches toward large families. In these searches, the sequence of AP, NACHT, MJ, and PH-NTPases detected each other with significant E-values. For example, the ...
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