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Find- ing additional predisposition factors may play a role in decision making in pregnancy, however it is less likely that one would choose invasive testing with a primary aim to investigate these. Therefore we assume that miss- ing these findings is not the most important incentive for ...
全外显子组测序显示,OEC常见的分子突变包括CTNNB1、PTEN基因突变以及微卫星不稳定(microsatellite instability,MSI)[20]。dMMR或POLE突变(15%)、HRD(19%)、BRCA1/2突变(6%)及PIK3CA突变(31%)。在疾病早期出现的分子突变可为OEC早期诊断提供依据。 OEC...