[5]Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363:1693–703. doi: 10.1056/NEJMoa1006448 [6]Kinno T, Tsuta K, Shiraishi K, et al. Clinicopathological features of nonsmall cell lung carcinomas with BRAF...
非小细胞肺癌(NSCLC) 大部分的肺癌是非小细胞肺癌(Non small cell lung carcinoma,NSCLC)治疗和预后通常相似。NSCLC的主要亚型是: 肺腺癌(Adenocarcinoma of the lung)在吸烟者中更常见,女性比男性更常见,比其他类型的肺癌更容易发生在年轻人中。 细支气管肺泡癌(bronchioloalveolar carcinoma,BAC)该腺癌亚型发生在吸...
原发性肺癌是我国最常见的恶性肿瘤,从病理和治疗角度,肺癌大致可以分为非小细胞肺癌(non small cell lungcancer,NSCLC)和小细胞肺癌(small cell lung cancer, SCLC)两大类,其中NSCLC约占80%～85%,包括腺癌、鳞癌等组织学亚型,其余为SCLC。本文主要从原发性肺癌的危险因素、临床表现、肿瘤标记物、基因检测、治疗原...
Lung NeoplasmsInterleukin-12AdultAgedBackground Non small cell lung cancer (NSCLC) is a leading cause of cancer death. We have shown previously that IL-12rb2 KO mice develop spontaneously lung adenocarcinomas or bron...
[1]Rusch VW, etal. Induction chemoradiation and surgical resection for superior sulcus non-small-cell lung carcinomas: long-term results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160). J Clin Oncol. 2007 Jan 20;25(3):313-8. ...
[1].NCCN Clinical Practice Guidelines in Oncology(NCCN Guidelines®):non-Small-Cell Lung Carcinoma 2022V3. [2].Zhou CC, et al. Sugemalimab versus placebo, in combination with platinum-based chemotherapy, as first-line...
Pie chart showing incidences of non-small cell lung cancers as compared to small cell carcinoma shown at right, with fractions of smokers versus non-smokers shown for each type[2] 日前人们尝试各种疗法,希望对复杂的病情...
2018 CA Cancer发布全球范围内癌症统计数据显示肺癌仍是目前癌症死亡的主要原因。非小细胞肺癌(non-small cell lung cancer, NSCLC)约占肺癌的85%。腺癌(adenocarcinoma, AC)、鳞状细胞癌(squamous cell carcinoma, SCC)是NSCLC最常见的两种病理类型,其中AC和SCC约占70%。
参考文献:Lin YT, Li CF, Wu HC, Jan YH, Kuo YH. Case report: Heterogenous SMARCA4-deficient thoracic non-small cell lung carcinoma with various responses to nivolumab. Front Immunol. 2023 Mar 27;14:1131448. doi: 10.3389/fimmu.2023.1131448. PMID: 37051241; PMCID: PMC10083322....
参考文献:Lin YT, Li CF, Wu HC, Jan YH, Kuo YH. Case report: Heterogenous SMARCA4-deficient thoracic non-small cell lung carcinoma with various responses to nivolumab. Front Immunol. 2023 Mar 27;14:1131448. doi: 10.3389...