Nonetheless, application of atRA induced differentiation of NSC-34 cells and provides a suitable model to investigate molecular events linked to neurodegeneration of differentiated neurons.doi:10.1016/j.neuint.2013.03.008Oliver MaierJulia BhmMichael Dahm...
Stem Cell Differentiation Compound Library L80001593 化合物 产品详情 糖代谢化合物库 Glycometabolism Compound Library L25201196 化合物 产品详情 抗癌化合物库 Anti-Cancer Compound Library L21009019 化合物 产品详情 经典已知活性库 Bioactive Compound Library L400017760 化合物 产品详情 ...
CELL differentiationPhytocannabinoids, with their variety of beneficial effects, represent a valid group of substances that could be employed as neurogenesis-enhancers or neuronal differentiation inducers. We focused our attention on the neuronal-related potential of cannabichromene (CBC) when...
NSC-34 motor neuron-like cells are sensitized to ferroptosis upon differentiation.doi:10.1002/2211-5463.12577Alejandra M. MartinezJovan MirkovicZofia A. StaniszFahmida S. PatwariWan Seok YangFEBS Open Bio
The NSC-34 cell line is a widely recognized motor neuron model and various neuronal differentiation protocols have been exploited. Under previously reported experimental conditions, only part of the cells resemble differentiated neurons; however, they do not exhibit extensive and time-prolonged ...
of the in vitro injury model using the mechanical scratch method and to evaluate the effect of MLC901 in injured neuronal cells.#In this study, retinoic acid (RA) (1M and 10M) and 30M prostaglandin E2 (PGE2) induction was used to facilitate NSC-34 differentiation into motor neurons (MN)....
This was evidenced by the absence of neuronal cytoplasmic vacuolation and beading of neurites, which instead resulted in better neuronal differentiation. Enhanced lactate levels and increased expression of its transporter, MCT-1, with sustained expression of trophic factors, namely, GDNF and BDNF, by...
Knockdown of TDP43 inhibits neurite growth during neuronal differentiation of NSC-34 cells.Chunxing, YangWeijia, TanCatheryne, WhittleLinghua, QiuLucheng, CaoSchahram, AkbarianZuoshang, Xu
Then, the selection of positive clones and induction of differentiation of NSC-34 cells into motor neurons were performed using a differentiation medium consisting of DMEM-HG/HAM’S F12 (Biowest, Nuaille, France) (1:1), 10% heat-inactivated fetal bovine serum (FBS) (Biowest, Nuaille, ...
Nucleophosmin (NPM), a multifunctional nucleolar phosphoprotein is dysregulated in human malignancies leading to anti-apoptosis and inhibition of differentiation. We evaluated the precise three-dimensional structure of NPM based on the highly conserved structure of Xenopus NO38 and its requirement to form...