According to the selection of studies presented, a few drugs can be ranked, those with highest safety first: ibuprofen, tenidap, fenbufen, aceclofenac, indomethacin, ketorolac, diclofenac, tenoxicam, piroxicam and ASA.doi:10.1016/S0950-3501(98)80004-4Albrecht Wiebalck...
In a systematic review of 11 controlled epidemiologic studies comparing ibuprofen with other drugs, ibuprofen ranked lowest or equal to lowest in 10/11 studies for GI risks followed by diclofenac, while azapropazone, tolmetin, ketoprofen, and piroxicam ranked highest. Higher doses of ibuprofen ...