Thus, the epitope 5-1-1 from the three different strains are equivalent antigenic determinants and therefore are “copies” even though their sequences are not identical. In general the amino acid sequences of equivalent antigenic determinants will have a high degree of sequence homology, e.g.,...
to 26 Å on each side. Selected side chains (R24, K26, and T59 of DENV3; M1026, S1060, and Y1023 of ZIKV) were temporarily removed (equivalent of being temporarily mutated to alanine) to create more space during the initial IFD process and were restored after the docking step. The ...
Thus, the epitope 5-1-1 from the three different strains are equivalent antigenic determinants and therefore are “copies” even though their sequences are not identical. In general the amino acid sequences of equivalent antigenic determinants will have a high degree of sequence homology, e.g.,...