The aim of this study was to examine the possible association of single nucleotide polymorphisms in the NR1H4 gene with susceptibility to colorectal polyps, ulcerative colitis (UC) and CRC. Methods: A total of 284 patients (96 CRC, 144 polyps, 44 UC) at Peking Union Medical College Hospital...
pMD18-T载体是由pUC18载体改建而成的。在pUC18载体的多克隆位点处的XbaI和SalI识别位点之间插入了EcoRV识别位点,用EcoRV进行酶切反应后,在两侧的3’端添加“T”而成。这种构建方式使得pMD18-T载体非常适合于克隆PCR产物。 pMD18-T载体的优点 高效克隆PCR产物:pMD18-T载体的构建方式使得它非常适合于克隆PCR产物,可...
背景资料 提供的NR1H4人源重组蛋白(P01)产品为带有GST标签的人源NR1H4全长序列重组蛋白,其对应的GeneID号为9971。 产品描述 与其它公司提供的重组蛋白不同,该NR1H4人源全长重组蛋白(P01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的...
Ensembl Gene ID ENSG00000012504.15 Ensembl mRNA ID NR1H4-206 包装清单: 产品编号 产品名称 包装 QH07353S Human NR1H4 qPCR Primer Pair 1nmol each — 说明书 1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所...
CDS-H09035-1 pDonR223-NR1H4 GateWay 2ug/0.5ml ￥800 现货 CDS-H09035-2 pMD18-T-NR1H4 TA克隆 2ug/0.5ml ￥800-1500 1-2周NR1H4 重组病毒 货号产品名称Method规格价格货期 CDS-H09035-11 rAd-NR1H4 重组腺病毒 10^10cfu/支 ￥3000 3-5周 CDS-H09035-12 rAAV-NR1H4 重组腺相关病毒 10...
CDS-R06214-1 pDonR223-NR1H4 GateWay 2ug/0.5ml ￥0 现货 CDS-R06214-2 pMD18-T-NR1H4 TA克隆 2ug/0.5ml ￥0 1-2周NR1H4 重组腺病毒 货号产品名称Method规格价格货期 CDS-R06214-11 rAd-NR1H4 重组过表达腺病毒 10^10 vg/支 ￥2500 3-5周 CDS-R06214-12 rAd-sh-NR1H4 重组干扰腺病毒...
提供的AKT3单克隆抗体(M04), 克隆号4C1产品为小鼠源单克隆抗体,对应的抗体亚型为IgG2a Kappa。该基因又称DKFZp434N0250、PKB-GAMMA、PKBG、PRKBG、RAC-PK-gamma、RAC-gamma、STK-2,全名为v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)。对应Gene号为AF124141,其蛋白编号为AAD2908...
方法通过基因表达综合(Gene Expression Omnibus,GEO)数据库获取2份CAG芯片(GSE27411、GSE116312)基因表达样本,利用R语言筛选出CAG差异表达基因,获得CAG免疫相关基因进行基因本体论(gene ontology,GO)和京都基因与基因组百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)分析。利用STRING数据库构建蛋白质-蛋白质相互...
背景资料This gene encodes a ligand-activated transcription factor,which shares structural features in common with nuclear hormone receptor family,such as a DNA-binding domain that targets the receptor to specific DNA sequences,and a ligand-binding domain,which interacts directly with the ligand and co...
(Supplementary Fig.3). AsNR1H4is most highly expressed in the liver, we then differentiated wild-type and mutant iPSCs to hepatocyte-like cells (hereafter described as hepatocytes). As FXR is a transcription factor, we used gene expression as a means of examining the impact of the R436H ...