◆加拿大区域可评3中等级的奖项:Zone,Provincial,National ◆加拿大的学校可以评Canadian Championship Plaque, Provincial Championship Plaques和Zone Championship Certificates 欧几里得数学竞赛考试内容 欧几里得数学竞赛的考试内容涵盖了代数与方程、数列、多项式、平...
阿尔兹海默症(Alzheimer Disease,AD)是一种神经退行性疾病,以记忆力、认知能力逐渐下降,并出现精神和行为异常为特征。AD常见的神经病理学变化是细胞外老年斑(Senile plaques, SP)和细胞内神经原纤维的缠结(Neurofibrillary tangles, NFTs)的...
Alzheimer's disease (AD) is the most abundant tauopathy and is characterized by Aβ-derived plaques and tau-derived tangles, resulting from the unfolding of the corresponding monomeric subunits into ordered β-sheet oligomers and fibrils. Intervening in the toxic aggregation process is a promising ...
Synthesis and Evaluation of 18F-Labeled 2-Phenylbenzothiazoles as Positron Emission Tomography Imaging Agents for Amyloid Plaques in Alzheimer’s Disease. J. Med. Chem. 2009, 52, 1428–1437. [Google Scholar] [CrossRef] Bertini, S.; Calderone, V.; Carboni, I.; Maffei, R.; Martelli, A.;...
研究背景: 阿尔茨海默症(Alzheimer''s disease,AD),俗称老年性痴呆,是常见的进行性神经退行性疾病.AD的两个典型病理学特征包括β淀粉样肽(Aβ)沉积形成的老年斑(senile plaques,SPs)和由异常过度磷酸化Tau蛋白聚集形成的神经原纤维缠结(neurofibrillary tangles,NFTs).除了老年斑和神经元纤维缠结两个典型病理学特征外...
The gate is designed in the traditional Chinese style of a three-bay, three-tiered archway, and has become a landmark of Cheeloo University. The plaques on the front and back of the gate, inscribed with "Cheeloo University" and "Alumni Gate", were written by Wang Shoupeng, then the dire...
It is characterized by the accumulation of amyloid β in the form of extracellular plaques and by intracellular neurofibrillary tangles. Genetic data, autopsy and neuroimaging studies in AD patients show Aβ plaque deposition precedes cortical tau pathology. Peripheral organs like liver, kidney play ...
is the predominant matrix component in atherosclerotic plaques. In this ... ER Andreeva,IM Pugach,AN Orekhov - 《Atherosclerosis》 被引量: 105发表: 1997年 [Pathogenesis of arteriosclerosis and aneurysm development of the infrarenal aorta and pelvic circulation after unilateral leg amputation]. Paes...
Amyloid senile plaques and tau neurofibrillary tangles are neuropathological hallmarks of Alzheimer's disease that accumulate in the cortical regions of the brain in persons with mild cognitive impairment who are at risk for Alzheimer's ... A Petric 被引量: 1492发表: 2006年 Therapeutic Doses of...
In active MS plaques, EBV-encoded RNA (EBER)-1 was the only and rarely detected transcript. The frequency of detected intrathecal anti-EBV antibody synthesis in patients with MS did not differ from that in non-MS inflammatory CNS disease control patients. Anti-EBV antibodies were detected in ...