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Bicell Scientific-抗-NPT2a(SLC34a1)抗体在小鼠组织上得到验证,并推荐用于啮齿动物和人类组织材料的免疫荧光标记、IHC或蛋白质印迹。 钠依赖性磷酸盐转运蛋白2A(NPTIa或NPT2a),也称为Na+-Pi协同转运蛋白2A(NaPi-2A)或SLC34a1,由人类中的SLC34a1基因编码。 NPTIa由8个跨膜结构域组成,在肾脏近端小管...
中文名 NaPi-4 (Npt2a) 英文名 NaPi-4 (Npt2a) 英文别名 NaPi-4 (Npt2a) 您刚刚浏览过 NaPi-4 (Npt2a) 刚刚更新的化工产品 69720-86-1 854662-85-4 79782-43-7 69721-08-0 854663-04-0 768370-07-6 697216-36-7 79782-45-9 69721-81-9 768387-36-6 69722-50-5 768387-39-9 78693-...
We hypothesized that regulation of apical membrane trafficking of Npt2a is dependent on actin cytoskeleton (AC) and SNARE protein interactions. To study AM trafficking, we first treated opossum kidney (OK) cells with parathyroid hormone to deplete Npt2a followed by treatment with low Pi medium (...
结果发现34岁的肾结石男患者和64岁的骨质疏松女病人有NPT2a基因突变。另外,那位女病人唯一的女儿的脊柱是畸形的,有手臂骨折史,血液中磷酸盐水平也较低,她也有该突变基因。实验室检查后研究者证实该突变基因在蛙卵中表达时功能异常。 “这项研究有其重要性,因为它把NPT2a基因广泛的动物和细胞模型文献和人类的生理...
The sodium phosphate cotransporter-2A (NPT2A) mediates basal and parathyroid hormone (PTH)- and fibroblast growth factor-23 (FGF23)-regulated phosphate transport in proximal tubule cells of the kidney. Both basal and hormone-sensitive transport require sodium hydrogen exchanger regulatory factor-1 (NH...
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We hypothesize that PTH stimulates Npt2a mRNA degradation through alterations in Roquin-2 and KSRP activity and/or expression. To address this hypothesis, we examined Roquin-2 and KSRP expression in opossum kidney (OK) cells, a proximal tubule cell culture model, treated with 100nM PTH for 15...