The knowledge of NPPA-AS1 (a new lncRNA) in cancer research is hardly known. Thus, it is of urgent need to study the underlying role of NPPA antisense RNA 1 (NPPA-AS1) in cervical cancer (CC). In this study, NPPA-AS1 was discovered to be lowly expressed and upregulation of it ...
The knowledge of NPPA-AS1 (a new lncRNA) in cancer research is hardly known. Thus, it is of urgent need to study the underlying role of NPPA antisense RNA 1 (NPPA-AS1) in cervical cancer (CC). In this study, NPPA-AS1 was discovered to be lowly expressed and upregulation of it ...
(P<0.05).lncRNA NPPA-AS1靶向调控miR-372-3p表达.抑制miR-372-3p显著降低SW480细胞的活力,使细胞的凋亡率增加,并降低了Bcl-2和cyclinD1的表达,提高了Bax和p21的表达(P<0.05).上调miR-372-3p表达逆转了过表达lncRNA NPPA-AS1对SW480细胞的影响.结论过表达lncRNA NPPA-AS1通过靶向下调miR-372-3p表达调控结...
Through a cardiac regeneration model by apical resection (AR) of the left ventricle in neonatal mice, we identified an lncRNA named natriuretic peptide A antisense RNA 1 (NPPA-AS1), which negatively regulated cardiomyocyte proliferation. In neonates, NPPA-AS1 deletion did not affect heart ...