Nox4 was down-regulated in renal arteries and Nox4-dependent H2O2 generation and endothelial relaxation were reduced in OZR. Up-regulation of both Nox2 and Nox1 was associated with augmented O2.- production but reduced H2O2 generation and blunted endothelial Nox2-derived H2O2-mediated in obese ...
RT-PCR gene expression analysis of Nox1, Nox4, Nox2, p47phox, Xanthine Oxidase (XO), eNOS and iNOS in the aortic sinus relative to 18S of control and diabetic ApoE-/- mice treated with or without GKT137831 (GKT) for 10weeks (60mg/kg/day). Data are Mean±SEM with N...
Expression of Nox1, Nox2, and Nox4 (gene and protein) and NAD(P)H oxidase activity were increased in SHR. Basal NAD(P)H oxidase activity was blocked by GKT136901 (Nox1/4 inhibitor) and by Nox1 siRNA in WKY cells and by siNOX1 and siNOX2 in SHR. Whereas Ang II increased ...
Porcine coronary smooth muscle expresses NOX1, NOX2, NOX4, and NOX5 isoforms.Hope K. A. GoleDarla L. TharpDouglas K. Bowles
NOX1NOX4Nrf2meloxicamneuroinflammationstressMeloxicam has shown significant neuroprotection in experimental models of stroke, Alzheimer's disease, and Parkinson's disease. However, the potential of meloxicam to treat depression-like neuropathology in a chronic restraint stress (CRS) model and the associated...
Braunersreuther V, Montecucco F, Ashri M, Pelli G, Galan K, Frias M, et al. Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury. J Mol Cell Cardiol 2013;64:99-107. http://dx.doi.org/10.1016/j.yjmcc.2013.09.007. [PMID: 24051369]....
Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHRAortaHypertensionHyporeactivityPregnancyReactive oxygen speciesAims: We determined whether decreased reactive oxygen species (ROS) production in the aorta of ...
Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expression contribute to hyporeactivity to phenylephrine in aortas of pregnant SHRdoi:10.1016/j.lfs.2015.12.011Jessica Antonini TroianoSimone PotjeMurilo GratonCristina Antoniali
Jaquet, "Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury," Journal of Molecular and Cellular Cardiology, vol. 64, pp. 99-107, 2013.Braunersreuther V, Montecucco F, Asrih M, Pelli G, Galan K, Frias M, Burger F, Quindere AL, Montessuit ...