Nox4 was down-regulated in renal arteries and Nox4-dependent H2O2 generation and endothelial relaxation were reduced in OZR. Up-regulation of both Nox2 and Nox1 was associated with augmented O2.- production but reduced H2O2 generation and blunted endothelial Nox2-derived H2O2-mediated in obese ...
Porcine coronary smooth muscle expresses NOX1, NOX2, NOX4, and NOX5 isoforms.Hope K. A. GoleDarla L. TharpDouglas K. Bowles
For this purpose, we investigated myocardial ischemia/reperfusion pathology in mice deficient in various \\{NADPH\\} oxidase isoforms (Nox1, Nox2, Nox4, as well as Nox1/2 double knockout). Following 30聽min of ischemia and 24聽h of reperfusion, a significant decrease in the size of ...
Together, the present findings prove the neuroprotective/antidepressant actions of meloxicam in CRS-induced depression by ameliorating hippocampal neuroinflammation and pro-oxidant changes, likely by modulating COX-2/NOX1/NOX4/Nrf2 axis.Arab, Hany H....
Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHRAortaHypertensionHyporeactivityPregnancyReactive oxygen speciesAims: We determined whether decreased reactive oxygen species (ROS) production in the aorta of ...
Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expression contribute to hyporeactivity to phenylephrine in aortas of pregnant SHRdoi:10.1016/j.lfs.2015.12.011Jessica Antonini TroianoSimone PotjeMurilo GratonCristina Antoniali
Braunersreuther V, Montecucco F, Ashri M, Pelli G, Galan K, Frias M, Burger F, Quindere ALG, Montessuit Ch, Krause K-H, Mach F, Jaquet V (2013) Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury. J Mol Cell Cardiol 64:99–107...
Braunersreuther V, Montecucco F, Ashri M, Pelli G, Galan K, Frias M, et al. Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury. J Mol Cell Cardiol 2013;64:99-107. http://dx.doi.org/10.1016/j.yjmcc.2013.09.007. [PMID: 24051369]....
meloxicam;stress;neuroinflammation;NOX1;NOX4;Nrf2 1. Introduction Major depressive disorder (MDD) is the most common neuropsychiatric disorder, and it has several serious consequences, including suicidal attempts [1]. The pathogenesis of MDD comprises increased stimulation of the hypothalamic–pituitary–...