“Dr Chang focused on how MRD can be monitored [in] clinical trials. I’m going to focus on regimens that are currently approved for frontline management of CLL, because I read the assignment.” Pro/Benefits Chang, instructor in the Department of Hematology and Medical Oncology at Winship...
The article reports on the efficacy of Erbitux to increase survival in advanced non-small lung cancer (NSCLC). Based on the First-Line Treatment for Patients with epidermal growth factor receptor (EGFR)-Expressing Advanced NSCLC (FLEX) trial versus chemotherapy, overall survival was 11.3 months for...
In 2017, the FDA approved the first CAR-T cell therapy for large B-cell lymphoma with upregulated CD19 surface protein and so far, four other CAR-T cell therapies have been approved by the FDA. It is an exciting time for cell therapies. The upcoming years will show whether current ...
Currently, the PD-1 inhibitor nivolumab (Opdivo) combined with the CTLA-4 inhibitor ipilimumab (Yervoy) remains the only approved immunotherapy combination. However, research into combination approaches is now focusing on triplets of antiPD-1 therapies and new checkpoints, such as IDO, Robert ...
The ski revolution of carving has been on its triumphant march worldwide for around 8 to 9 years. About 80% of all skiers now use carving skis and normal skis are hardly offered in the retail trade or by ski hire companies. The intense and controversial discussion of the past few years ...
Another challenge is that some drugs have been approved in the United States, but have not been approved overseas, or vice versa. Additionally, in many countries, direct-to-consumer advertising is illegal. Therefore, pharma companies need to determine how to communicate to consumers within the bou...