In the simple novel about a little mouse's adventure, the little mouse found a big piece of cheese in a corner of the old house. But it didn't eat it right away. What might be the reason? A. It wasn't hungry at that time B. It thought the cheese might be a trap C. It ...
Explore content About the journal Publish with us Sign up for alerts RSS feed nature scientific reports articles article Article Open access Published: 18 July 2019 A novel mouse tail lymphedema model for observing lymphatic pump failure during lymphedema development Michael J. Weiler, Matthew T. ...
Mouse models of RA have been critical for understanding the underlying genetic and cellular mechanisms of pathogenesis [25–27]. Both induced and spontaneous models have been developed. In the most common experimentally induced models, injection of adjuvant and various joint matrix components, such as...
In addition, we identified several homologous mouse EST clones. Two were obtained and se- quenced. One clone (AA869195) was about 0.8 kb and se- quence analysis indicated that it was a partial clone. The other clone (AI747122) was about 2.9-kb long and was sequenced completely. The ...
We found that delivery of the RhoR2 by scAAV2/9 is capable of restoring vision to rhodopsin knockout mice, and rescuing our novel transgenic huRhoP347S mouse model of dominant RP. Average a-wave responses of RhoR2-injected eyes were 1.8-fold higher than those of control-injected eyes. We...
From the F1 generation, the mouse line was maintained by brother-to-sister mating. A novel mouse strain was established over >20 continuous generations and designated the Institute of Radiation Medicine-2 (IRM-2) mouse. The biological characteristics, genetic characteristics and susceptibility to ...
These features in this mouse model are appropriate for cognitive assessment and genetic analysis, and it may provide a powerful tool to understand the pathophysiology of WM lesions. 展开 关键词: Animals Mice, Inbred C57BL Mice Neuroglia Astrocytes Microglia Cerebrovascular Disorders Carotid Stenosis ...
Human hypervariable minisatellites provide highly informative loci for analyzing processes of tandem repeat turnover, but little is known about mechanisms of instability in other species. We have therefore screened the mouse genome for analogous VNTR loci. One of the probes we isolated, MMS10, detect...
Drebrin A, a major neuronal actin-binding protein, regulates the dendritic spine shapes of neurons. Here, we have cloned and characterized a novel mouse cDNA clone encoding a truncated form of drebrin A, named s-drebrin A. Analysis of the genomic organization of the mouse drebrin gene ()...
(b) A pulled glass micropipette is broken to provide a sharp tip with an opening of about 100 µm. (c) To perform mousetap, the foot activated pump is set on aspirate, the eye is proptosed and held firm by the thumb applying gentle pressure 180° from the injection site, the ...