Starting from 4, two new routes to 1,3,5-hexatriene 1 has been developped, namely by treating the bistosylate derivative of 4 with sodium iodide in 2-(2-ethoxy-ethoxy) ethanol (adaptation of Linstead's reaction) and by a modification of Corey's method, where 4 is treated with N′, ...
ExerciseSignal TransductionMechanotransduction, CellularMechanical stress on the heart can lead to crucially different outcomes. Exercise is beneficial because it causes heart muscle cells to enlarge (hypertrophy). Chronic hypertension also causes hypertrophy, but in addition it causes an excessive increase ...