Any animal demonstrating evident signs of suffering or affected by a body weight decrease > 20% from the beginning of the study would be euthanized. 2.2. Drugs Paclitaxel powder (PTX; LC Laboratories, Woburn, MA, USA) was dissolved in a vehi- cle solution composed of 10% tween 80, 10% ...
Furthermore, accelerated infection in vivo observed in vaccinated pigs was evidenced by earlier onset of clinical signs, viremia and death compared to the non-vaccinated, challenge controls. An earlier onset of disease in immunized animals following virulent challenge has been previously observed for ...
Although it was assumed that the virus titer applied was equivalent, mice infected intradermally died more rapidly whereas mice infected by tick bites did not show clinical signs, hence indicating the absence of a SAT effect. One reason might be the suppression of migration of macrophages and ...