Thyroid peroxidase antibodies (TPOAb): The type of antibody is detected in 95% of people with Hashimoto's and around 70% of those with Graves' disease.7A high TPOAb is also seen after childbirth in people withpostpartum thyroiditis. Thyroid-stimulating hormone receptor antibodies (TRAb): These...
Association of thyroid peroxidase antibodies with the rate of first-trimester miscarriage in euthyroid women with unexplained recurrent spontaneous abortion. Front Endocrinol (Lausanne) 2022 Aug 31;13:966565. doi: https://doi.org/10.3389/fendo.2022.966565. PMID: 36120428; PMCID: PMC9471195. Meng LH...
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(1973). The concentra tion of peroxidase in normal and adenomatous human thyroid tis sue with special reference to patients with Pendred syndrome. Acta Endocrinol. 72: 171-178.Ljunggren , J. G., Lindström, H., Hjern , B.: The concentration of peroxidase in normal and adenomatous...
根据甲状腺过氧化物酶抗体(thyroid peroxidase antibodies,TPOAb)是否阳性分组,建立参考值范围,所有过程均参照临床实验室标准协会文件CLSI EP28⁃A3。结果共纳入符合标准的TPOAb阴性组孕妇14 332 例,TPOAb阳性组孕妇10 254例。两组孕妇均孕早期TSH中位数水平最低,孕晚期最高,孕中期处于两者之间,趋势一致。本研究...
Characterization of the thyroid microsomal antigen, and its relationship to thyroid peroxidase, using monoclonal antibodies. MAb directed to the thyroid microsomal antigen have been developed. All bound to 101- and 107-kD bands in Western blot analysis using thyroid microsomal fr... L Portmann,FW ...
Women with a known non-thyroid cause of TSH elevation, those treated with anti-thyroid drugs, amiodarone, lithium, and those with a history of thyroidectomy, neck radiotherapy and 131I treatment were excluded. Seventy women had negative antithyroperoxidase antibodies. Ultrasonography revealed a eu...
(Life Technologies). Membranes were probed with primary antibodies overnight on a 4 °C shaker, then incubated with horseradish peroxidase (HRP)-conjugated secondary antibodies, and signals were visualized with ECL (Bio-Rad). The primary antibodies targeting the following proteins were used: β-...
Findings In this randomized clinical trial involving 600 women undergoing in vitro fertilization and embryo transfer who tested positive for antithyroperoxidase antibodies but who had a normal thyroid function, the miscarriage rate before 28 weeks’ gestation was 10.3% among women who received and 10.6...
An elevation of serum TSH level (6.10 mUI/l, n.v. 0.4– 4.4 mUI/l) with normal fT3 and fT4 levels was found; further analyses revealed antithyroid antibodies (antithyroid peroxidase, 342 kU/l, n.v. o40 kU/l), not associated with morphological abnormalities, leading to medical therapy ...