To diagnose heart failure with preserved ejection fraction (HFpEF), the following three criteria have to be fulfilled [1–8]:...
On the regulation of sex-hormone-binding globulin – a challenge of an old dogma and outlines of an alternative mechanism. J Steroid Biochem. 1989;32:327–34. Google Scholar Pasquali R, Casimirri F. The impact of obesity on hyperandrogenism and polycystic ovary syndrome in premenopausal ...
M. Tinnitus in 7-year-old children. Eur. J. Pediatr. 162, 276–278 (2003). PubMed Google Scholar Coelho, C. C. B., Sanchez, T. G. & Tyler, R. S. Tinnitus in children and associated risk factors. Prog. Brain. Res. 166, 179–191 (2007). Article Google Scholar Bulbul, S...
However, the rate is very low, about 1% per year, clearly not enough to provide significant CM replacement. Hypertrophy of remaining CMs does occur after the loss of a portion of the myocardium due to ischemic damage or other major cell loss [141,142]. Additional pressure overload, volume ...
One of the most significant challenges is that the D4Z4 macrosatellite and the DUX4 gene are specific to Old World primates [17,18]. Moreover, the proper chromosomal context of the FSHD locus is crucial in the disease [46,63]. Unfortunately, murine Dux only shares partial sequence and ...