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Prostate cancer (PCa) is the second most frequent malignancy (after lung cancer) in men worldwide1. The most common diagnostic procedures for diagnosing PCa for over 30 years have been physical examination (i.e., the digital rectal examination), serum prostate specific antigen (PSA) levels, im...
Lastly, all patients with PsA were under treatment with NSAIDs and methotrexate. In five patients (9.8%) the diagnosis of IJD was established 3–6 months after the development of the aforementioned symptoms. 3. Methods CMR examinations were performed using a 1.5 T and 3.0 T scanners. The ...
After tumor development, mice were irradiated with X-rays in the presence or absence of MnPs. MnP treatment continued until animals were sacrificed or died. We found that MnP treatment, when combined with radiation, significantly enhanced the antitumor effect of radiation and promoted overall life ...
Studies in breast cancer cell lines have shown that stem cell populations are more resistant to radiation treatment and that Wnt/β-catenin signaling mediates resistance [140-142]. Recent work by the Rosen lab evaluated radiation resistance in CSCs isolated from p53-null mouse mammary tumors [143...
One problem that arises with the diagnosis and treatment of prostate cancer is that PSA levels and Gleason score are not perfect at determining prostate cancer’s prognosis [7,8]. Particularly for prostate cancers with an intermediate Gleason score, it can be hard to determine the cancer’s pro...