In total, 500 nM AGN194310 reduced cell numbers by ∼80% in the cultures of the three prostate carcinoma lines and the patient's primary cells, and it had no effect on the normal prostate epithelium cells. The prostate carcinoma cell lines were approximately four times as sensitive to ...
meaning non-diploid copy numbers in autosomes and a non-diploid copy number state in chrX for female samples and non-haploid chrX for male samples. In the case of prostate samples, we then classified all the cells with no alterations as diploid; cells with less than 25% of the genome alte...
Most breast, lung, colon, skin, and prostate cancers are carcinomas. This class includes the two most common skin cancers, basal cell carcinoma and squamous cell carcinoma. Also in this class is the glandular cancer adenocarcinoma. What Is Sarcoma Cancer? Sarcomas occur in connective tissue like...
lung, colon, skin, and prostate cancers are carcinomas. This class includes the two most common skin cancers, basal cell carcinoma and squamous cell carcinoma. Also in this class is the glandular cancer adenocarcinoma.
(1), prostate (1), renal cell (1) 6 Uncertain Clinical Actionability BARD1 3 Pancreatic (1), prostate (1), renal cell (1) 3 CHEK2c 11 Bladder (1), breast (1), endometrial (1), pancreatic (2), prostate (5), renal cell (1) 11 FAM175A 0a Pancreatic (1) 1 RAD50 1 ...
Cyclophosphamide creates a receptive microenvironment for prostate cancer skeletal metastasis Cancer Res., 72 (2012), pp. 2522-2532 View in ScopusGoogle Scholar 16 P.B. Johansen Doxorubicin pharmacokinetics after intravenous and intraperitoneal administration in the nude mouse Cancer Chemother. Pharmacol.,...
In our models, the comparison of histologically normal tissue in EAC patients versus controls benefitted from good sample numbers prechemotherapy and gave a strong signature (AUROC = 1) with highly elevated 3-hydroxybutyrate, succinate, and formate and somewhat increased acetate, lactate, ADP, and ...
We use analysis of features from HE stained histological images of normal mouse prostate epithelium, distinguishing the descriptors for variability between ventral, lateral, and dorsal lobes. In addition, we use two common prostate cancer models, Hi-Myc and Pten+/− mice, to build a feature-...
The proportion of truncating mtDNA mutations within normal colorectal clones and colorectal cancer tissues. Two-sided Fisher’s exact test.f, Distributions of mtDNA copy numbers in normal colorectal clones and matched cancer tissues among 19 individuals. Boxplots illustrate median values with IQRs and...
prostate and its over-expression in neoplastic prostate epithelium. Once activated, the serine protease domain oftmprss2is released from the cell surface into the extracellular space and activates PAR (protease-activated receptor)-2 that has a role in prostate cancer and tumor metastasis [70]. ...