CONCLUSIONS: HPV-pos/cyt-neg women continue to have an increased CIN3+ risk, also when the repeat HPV test is negative. Therefore, intervals in primary HPV screening should be determined separately for HPV-positive and -negative women.British Journal of Cancer advance online publication 7 ...
Methods Pap smear samples were obtained from 60 HPV-positive (HPV-16/18) patients with histologically confirmed severe dysplasia (cervical intra-epithelial neoplasia (CIN 3) or carcinoma in situ) and the normal cytology group. The expression of hsa-miR-194-5p and hsa-miR-195-5p was analyzed ...
a and b expression analysis indicated a significant down-regulation of hsa-miR-194-5p (fold change: -2.628, P < 0.0001) and hsa-miR-195-5p (fold change: -1.584, P < 0.0001) in the HPV-Positive patients with severe dysplasia compared to normal cytology controls (median, mean, ...
De Sanjosé, SilviaBruni L, Diaz M, Castellsague´ X, Ferrer E, Bosch FX, de Sanjose´ S. Cervical HPV prevalence in five continents: meta-analysis on one million women with normal cytology. J Infect Dis 2010; 202: 1789-1799....
inPrep Pap samples. Age-specific detection of high risk HPV DNA in cytologically normal, computer-imaged ThinPrep Pap samples.Age-specific detection of high risk HPV DNA in cytologically normal, computer-imaged ThinPrep Pap samples.Cytology
5 A cross-sectional evaluation of the HPV DNA prevalence in 13 countries estimated that 6·6% of women in the age-range 15–74 years with normal cytology are carriers of HPV DNA, with marked variation within and between world regions (range 1·4–25·6%).6 Therefore, HPV can be ...
RESEARCH ARTICLE Open AccessRisk of cervical lesions in high-risk HPVpositive women with normal cytology: aretrospective single-center study in ChinaZhiling Wang 1 , Ting Liu 1 , Yunjian Wang 2 , Ying Gu 1 , Hui Wang 1 , Jingkang Liu 1 , Baoxia Cui 1 and Xingsheng Yang 1*Abstract...
Distribution of hrHPV genotypes in cervical cytology Of the 56/171(32.7%) women who tested positive for hrHPV, only 8/56 (14.3%) had cervical pre-malignant lesions. One with ASC-H had HPV58. Of the four women with ASCUS, two tested positive for HPV56, one for HPV35 and the ...
The probability for a Pap test to be abnormal is directly proportional to HPV viral load: results from a Swiss study comparing HPV testing and liquid-based... In a study involving 13842 women and 113 gynaecologists, liquid-based cytology and HPV testing for detecting cervical cancer were compare...
结论 宫颈高度病变患者部分存在宫颈细胞学检查正常,对于具有可疑临床表现的患者联合HPV检测、阴道镜检查及宫颈活检术能大大提高宫颈病变的诊断效率,从而为临床早期诊断和治疗提供有效依据。 英文摘要: Objective To analyze the predictive values of ThinPrep cytology test(TCT),high risk human papilloma virus(HPV) ...