The ideal would be to study local vaginal oestradiol, glycogen and the bacterial composition. Wider implications of the findings: In contrast to previous studies in menopause where low oestrogen levels associate with the vaginal microbial composition, this study uses the high oestradiol environment of ...
Five out of 6 normally-menstruating women who were treated with a potent gonadotropin-releasing hormone (Gn-RH) agonist in order to achieve medical hypophysectomy developed hot flushes despite having normal oestradiol (E2) levels. The Gn-RH agonist was administered subcutaneously for 6 days and then...
We first explored the impact of the menopause in rats and then investi- gated the hypothesis that MT could reverse bone loss and ameliorate bone metabolism at both early and late stages. Furthermore, we investigated whether MT increased osteogenesis of bone marrow mesenchymal stem cells (BMSCs)...
Therein, it adopts a new keystone position in supporting the establishment and maintenance of pregnancy through its production of progesterone. Once the ovary has exhausted its reserve of follicles throughout reproductive life, many of its functions are lost as women enter the menopause. This Chapter...
Members of the p160 steroid receptor cofactor family, including AIB1 (Amplified in Breast Cancer 1) (also known as SRC-3/RAC3/ACTR/pCIP/TRAM-1), are of interest in endometrial carcinoma as they affect the function of estrogen (ER) and progesterone recept