The data obtained indicate that the five-fold increase of the tryptase+ MCs at the fibrotic border of the wound within the first 10 days is the result of increased recruitment/survival of MCs or MC precursors, but not of increased local proliferation. Recruitment of MCs is paralleled by the ...
Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus The mast cell plays a pivotal role in the early asthmatic response via release of mediators, which directly influence airway smooth muscle tone. Canine mas... PRA Johnson,AJ Ammit,SM Carlin,... - 《European...
Meineke V, Frungieri MB, Jessberger B, Vogt H, Mayerhofer A (2000) Human testicular mast cells contain tryptase: increased mast cell number and altered distribution in the testes of infertile men. Fertil Steril 74:239–244 Article PubMed CAS Google Scholar Meinhardt A, Bacher M, McFarlane...
The action of mast cell can be pro or anti-tumor depending on the mediators released into the microenvironment [10–12]. Among these mediators, stand out pro-angiogenic factors, such as heparanase and vascular endothelial growth factor (VEGF) and tryptase and chymases that provide tumor growth....
Activation of pulmonary mast cells by bronchoalveolar allergen challenge: in vivo release of histamine and tryptase in atopic subjects with and without asthma Am Rev Respir Dis (1988) AJ Wardlaw et al. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma—relationship to...
Cell cultures were examined every 2 weeks for total and mast cell number and cell differential using Wright Giemsa and acid toluidine blue stains and antibodies to mast cell tryptase and chymase, cell-associated histamine, and expression of CD34,c-kit, FcRI, and Fc纬RII using flow cytometric ...
Fraki JE. Immuno- peroxidase and enzyme-histochemical demonstration of human skin tryptase in cutaneous mast cells in normal and mastocytoma skin. Arch Dcrmatol Res 1988:280:363-70.Harvima, I. T., Naukkarinen, A., Harvima, R. J. and Fra¨ki, J. E. (1988). Immuno- peroxidase and...
clonal mast cellmastocytosisskintryptaseBackgroundPatients with elevated basal tryptase (sBT) >15g/l and anaphylaxis may have an underlying mastocytosis. A monoclonal mast cell activation syndrome with aberrant mast cells (MC) at extracutaneous sites has been described in patients with severe ...
Introduction The most commonly described pathway of anaphylaxis involves IgE mediated mast cell activation. Here we present three patients with elevated histamine, normal tryptase, and normal IgE. These findings suggest a non-mast-cell mediated pathway of anaphylaxis. All patients were placed on a ...
Various classes of proteins were found either to be present or to be upregulated in keloid tissue: (i) inflammatory/differentiated keratinocyte markers: S100 proteins, peroxiredoxin I; (ii) wound healing proteins: gelsolin-like capping protein; (iii) fibrogenetic proteins: mast cell 尾-tryptase, ...