Lactic acidosis occurs from an overproduction of lactate or decreased metabolism. It is common in critically ill patients, especially those with hematological conditions such as multiple myeloma, leukemia, and lymphoma. There are two types of lactic acidosis, Type A and Type B, with Type B ...
Increase in anions may be too low to push the anion gap out of the reference range in lactic acidosis, the clinical disorder can be severe but the lactate may not be grossly high (eg lactate of 6mmol/l) and the change in the anion gap may still leave it in the reference range admini...
The initial ABG was pH 7.32, pCO_2 34.5, pO_2 347, with a bicarbonate of 17.3 mEq/L. The lactate was 4.6 mEq/L. The serum AST was 27 IU/L and the ALT was 14 IU/L. The urine toxicology screen was negative, and the aspirin level was less than 2 mg/dL. Four hours after ...