The aim of the present study was to investigate the effect of low-normal and high-normal levels of IGF-1 in growth hormone (GH) deficient adults on cognition and wellbeing during GH treatment. A randomized, open-label, clinical trial including 32 subjects receiving GH therapy for at least ...
Background: Current guidelines state that the goals of growth hormone (GH) therapy in adults should be an appropriate clinical response, avoidance of side effects, and an IGF-1 value within the age-adjusted reference range. There are no published studies on the target level for IGF-1 that ...
The aim of the present study was to investigate the effect of low-normal and high-normal levels of IGF-1 in growth hormone (GH) deficient adults on cognition and wellbeing during GH treatment. A randomized, open-label, clinical trial including 32 subjects receiving GH therapy for at least ...
Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatmen... OBJECTIVESerum IGF-I levels are monitored during GH replacement treatment in adults with GH deficiency (GHD) to guide GH dose adju...
The effect of pegvisomant-induced serum IGF-I normalization on serum leptin levels in patients with acromegaly In humans, serum leptin correlates positively with fat mass. GH is lipolytic and patients with active acromegaly have lowered serum leptin compared to age,... C, Parkinson,AJ Whatmore,...
Leger J, Noel M, Limal JM, Czernichow P. Growth factors and intrauterine growth retardation. II. Serum growth hormone, insulin-like growth factor (IGF) I, and IGF-binding protein 3 levels in children with intrauterine growth retardation compared with normal control subjects: prospective study fr...
Comparing differences in the expression levels of GABPB1-AS1 between THP-1 cells and normal HS-5 cells. *p < 0.01. Full size image Discussion Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. According to the WHO classification, patients with recurring cy...
Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens The influence of varying dietary proteins levels from 0% to 18%, which is the level of dietary protein requirement, on plasma IGF-I concentration and tissu... K Nagao,K Hiramatsu,A Tsukada,... - 《...
As described above, EVs can stimulate angiogenesis, and transfer growth factors such as vascular endothelial growth factor, hepatocyte growth factor [231], insulin-like growth factor-1 (IGF-1), adrenomedullin, and stromal cell-derived factor-1 (SDF1) [4]. Horizontal transfer of the IGF-1 ...
Chan, E. Y.&Maclennan, I. C.(1993) Only a small proportion of splenic B cells in adults are short-lived virgin cells.Eur. J. Immunol.23, 357–63. CASPubMedGoogle Scholar Chan, S. H., Cosgrove, D., Waltzinger, C., Benoist, C.&Maths, D.(1993) Another view of the selective...