LDL/HDL cholesterol ratioNonalcoholic fatty liver diseaseBackground Low-density lipoprotein to high density lipoprotein (LDL/HDL) cholesterol ratio has been reported to predict the risk of many metabolic diseases. However, the association between the LDL/HDL cholesterol ratio and nonalcoholic fatty ...
Not all cholesterol is bad. High-density lipoprotein (HDL) cholesterol is considered "good" cholesterol because it actually works to keep the LDL, or "bad" cholesterol from building up in your arteries. The higher the HDL, the better. HDL levels of 60 mg/dL and higher can help reduce you...
HDL has the ability to remove the cholesterol from macrophage foam cells through reverse cholesterol transport, the main anti-atherogenic mechanism. Lipids that form the atherosclerotic lesion come mainly from low-density lipoprotein (LDL) cholesterol, and several studies proposed oxidative modification of...
one of which involves 12-LO and each of which can be inhibited by normal HDL, and b) HDL from at least some coronary artery disease patients with normal blood lipid levels is defective both in its ability to prevent LDL oxidation by artery wall cells and in its ability to inhibit the bi...
During gestation LDL size significantly decreased (P < 0.001), due to reduction in relative proportion of LDL I (P < 0.01) and increase of LDL II (P < 0.001) and IIIA (P < 0.05) subclasses. In the same time, HDL size and proportions of HDL 2a particles significantly decreased (P <...
Cholesterol and stroke - study shows that patients with low levels of HDL cholesterol and normal levels of LDL cholesterol are at greater risk of a stroke - Brief Article
Changes in LDL size and HDL concentration in normal and preeclamptic pregnancies. Atheroscle- rosis 2002;162(2):425-32.Belo L, Caslake M, Gaffney D, Santos-Silva A, Pereira L, Quintanilha A, et al. Changes in LDL size and HDL concentration in normal and preeclamptic pregnancies. ...
In the study correlation between LDL size and parameters such as BMI, age, sex, triglyceride, HDL-C and diabetic status was also investigated. Results: Based on results obtained, 59% of diabetic patients and 27% of controls showed LDL pattern B. LDL size was significantly lower in diabetics...
Although pravastatin did not significantly influence median apolipoprotein(a) levels, it significantly reduced mean cholesterol, LDL cholesterol and triglyceride levels and increased mean HDL cholesterol levels compared with placebo (p < 0.001); the maximal pravastatin effect was reached 3 to 4 weeks ...
Macrophages take up oxidized-LDL, and its increased cellular concentration activates LXRs, which induce the efflux of intracellular cholesterols from macrophages to serum apolipoproteins in the form of HDL, which then returns to the liver in a process termed reverse cholesterol transport. This process...