EXP3174 reached higher plasma concentrations and was eliminated more slowly than its parent compound; its levels paralleled the profile of angiotensin II blockade closer than losartan. Inhibition of the pressure response was dose dependent. The Hill-shaped relationship between response and EXP3174 ...
Mechaeil, Gard, Jackson, and Rusted (2011) reported that an acute 50-mg dose of losartan increased nonfocal prospective memory performance, although this effect was observed in normotensive younger adults. However, in a group of hypertensive older adults, Hajjar et al. (2012) found that 12 ...