tumor-infiltrated macrophages universally expressed immune checkpoint (IL4I1)18, M2 polarization-related (SPP1)5,19, and inflammatory genes (CCL7,ADAMDEC1, andSLAMF9), whereas dendritic cells in tumors were found to exhibit elevated expression ofCCL19andLAMP3, which are associated with inflammator...
Central curve shows the median of all histogram curves. Shades show 50, 80, and 100% of all histograms. Gray line indicates uniform distribution. e No other method tested could recover uniformly distributed null P values for co-expression, as measured by the violin plot of P values of KS ...
To generate Kaplan–Meier curves for TCGA and CGGA patients, all samples labeled recurrent, secondary, or normal tissue were removed. Duplicate samples were also excluded so that each patient was represented by exactly one sample. Kaplan–Meier curves were drawn by the Python package lifelines (Pyt...
These statistical tests were performed using SciPy Python library [23]. p<0.05 was considered significant for all statistical tests. A Bonferroni correction was applied for multiple comparison testing. To test whether AUCs of different ROC curves differ significantly, the AUCs were compared using R ...
Figure 5. Loss of Ultraconserved Ventral Forebrain Enhancers Results in Growth and Brain Abnormalities (A) Growth curves for males wild-type (WT, black) or hemizygous null (KO, red) for the ventral forebrain enhancers. Solid lines show mean weight, with dashed lines indicating SEM. Sample sizes...
Different lowercase letters in the same column indicate significant differences (P < 0.05). Both the rarefaction and Shannon curves of fungi and bacteria have reached a plateau (Fig. 1), indicating that the species in beef jerky did not increase significantly with the increase of sequencing ...
This considered both the non-lethal changes in host feeding rates and the lethal effects driving host mortality. To ascertain the temperature dependence of parasite effects on feeding rates and survival curves of snail hosts, we meticulously conducted a fully factorial laboratory experiment, ...
Let's say I have something in the mask, say gradient or BW copy of a specific layer or part of. Now, I decide to that it's not enough, in Gimp I could attach levels or curves and fix these (move black point or white point, or anything) to suite my needs. Another example is...
Precision Recall (PR AUC) curves (Fig.1b; Supplementary Dataset2; Supplementary Fig.7). To further analyze the strengths and weaknesses of each tool in addition to evaluating the PR/ROC AUC scores, we compared their positive predictions in more detail using six biological replicates of ...
We obtained the normal and abnormal labels from the majority vote of three radiologists (see “Labels” section in “Methods”). The percentage of abnormal images were 24% and 71% in DS-1 and CXR-14, respectively (Table 1). The areas under receiver operating characteristic curves (area ...