Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin... Signs of Diabetes
administration of C-peptide in high dose (70 nmol/kg), but not in low dose (7 nmol/kg), caused a significant delay in arteriolar and venular thrombus growth in normal and diabetic mice. This effect was repressed by cremaster muscle superfusion with insulin (100 microU/ml) in diabetic ...
This set of guidelines was the first to consider the use in HFNEF of tissue Doppler imaging (TDI) and natriuretic peptides (NP). The diagnosis of HFNEF required signs or symptoms of HF, an LVEF >50%, an LVEDVI <97 ml/m2, and evidence of diastolic LV dysfunction. Only cardiac ...
a, Graphical representation of the OGTT.b–i, Blood glucose (b) as well as plasma C-peptide (c), insulin (d), glucagon (e), adrenaline (f), noradrenaline (g), cortisol (h) and growth hormone (i) during an extended (6 h) OGTT. *Difference between TBC1D4 carriers and Controls ...
Modern medicine emphasizes the concept of homeostasis, constancy of the intern milieu. Accordingly, it is assumed that biological functions and processes are relatively stable during the 24 h and other time periods and that the exacerbation of disease an
The aorta contains numerous cell types that contribute to vascular inflammation and thus the progression of aortic diseases. However, the heterogeneity and cellular composition of the ascending aorta in the setting of a high-fat diet (HFD) have not been
To elucidate differences between the normal and the tendinopathy cohorts, we ran differential gene expression (DGE) analysis using MAST.12 Many mitochondrially expressed genes (MEGs) were found to be enriched in the normal cohort (Figure 2A). Genes related to cell motility and insulin-like growth...
This decline in glucose tolerance is also evident in the National Health and Nutrition Examination Survey III (20). The cause for the higher prevalence of impaired glucose tolerance (IGT) and type 2 diabetes in elderly individuals is unknown. However, decreased insulin sensitivity...
Samples for RIA insulin, specific insulin and C peptide were assayed in duplicate and for glucose in singleton. Definition and calculation of measures of insulin sensitivity. The effect of an increment in plasma insulin to enhance the fractional net disappearance of glucose from the extracellular ...
Concentrations of glucose and lactate in fluoride plasma were determined with the ADVIA Chemistry XPT clinical chemistry analyzer according to the hexokinase and colorimetric lactatoxidase method, respectively. Serum insulin, C-peptide and cortisol concentrations were measured with the ADVIA Centaur XPT ...