Blood urea nitrogen (BUN) level is another indicator of kidney function. Urea is a metabolic byproduct that can also build up if kidney function is impaired. The BUN-to-creatinine ratio generally provides more precise information about kidney function and its possible underlying cause compared with...
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Mean creatinine and BUN levels in the stable uremic and dialyzed sheep were 4.8/95 and 7.8/59 mg/dl, respectively. The other serum chemistries remained unchanged (mean values) from normal, although one sheep died of hypercalcemia (17.8 mg/dl). Renal blood flow correlated to GFR in both ...
Somatic cells accumulate genomic alterations with age; however, our understanding of mitochondrial DNA (mtDNA) mosaicism remains limited. Here we investigated the genomes of 2,096 clones derived from three cell types across 31 donors, identifying 6,451 mtDNA variants with heteroplasmy levels of≳0.3...
β-Endorphin was measured by radioimmunoassay in post-mortem human brains. Samples of brain were taken from five discrete areas, both from control brains and brains of schizophrenic patients. No difference in β-endorphin levels was found in these two groups of brains. β-Endorphin was confirmed ...
AML, T-ALL, and B-ALL leukemias and its levels in B-ALL correlate with poor survival. SMYD2 knockdown results in apoptotic death and loss of anchorage-independent transformation of each of these hematopoietic leukemias. These data provide an underlying mechanism by which SMYD2 acts during normal...
Creatinine clearance can also be more directly measured by collecting a 24-hour urine sample and drawing a blood sample. The creatinine levels in both urine and blood are determined and compared. Blood urea nitrogen (BUN) level is another indicator of kidney function. Urea is a metabolic byprod...
In laboratory tests, both female and male subjects showed higher baseline BUN, total cholesterol, and LDL-C levels, and lower eGFR levels in the higher quartiles. The prevalence of proteinuria was higher in the higher quartiles in females, whereas it was not different across the quartiles in...