Heparin anticoagulant activity estimated by the APTT disappeared faster than heparin anticoagulant activity estimated by the anti-Xa activity in the first phase. As expected, higher anticoagulant levels with the
To confirm RagHemoA phenotype, the clotting time of mouse plasma was determined by activated partial thromboplastin time (aPTT) using a semiautomated coagulometer (BioMerieux, France). FVIII assays The concentration of human FVIII was determined in mouse plasma by an enzyme-linked immunosorbent assay...
The efficacy of heparin treatment can be evaluated by measurement of the activated partial thromboplas-tin time or the whole-blood clotting time. A prolonga-tion of the APTT or whole-blood clotting time to 150% of their pre-dialysis values is recommended [20]. Individual dosing schedules can...
As a result, it has a dose-dependent increase in activated human partial thromboplastin time (aPTT) at doses up to 10 times greater than those needed to inhibit FXIIa by greater than 90%, with no effect on prothrombin time (PT). The PCB + FXII900 group was the only group in which ...
A multiple linear regression equation with hematocrit and baseline APtt as independent variables yielded a multiple correlation coefficient of 0.875 (p < 0.01). Thus, it may be possible to predict the APTT value produced by a given concentration of heparin in an individual subject from the subject...
PL-independent CT included chromogenic anti-factor Xa (anti-FXa), thrombin time (TT) and an assay to diagnose heparin-induced thrombocytopenia (anti-heparin-PF4). Results: Transient prolongation of PT, aPTT, DRVVT, ACT and SCT occurred in plasma samples obtained from NHVs in the phase 1 ...
CT scan with contrast showed clear dilatation and thrombosis of the right ovarian vein with spread to the IVC. Anticoagulant treatment was started with 1000 intravenous units of heparin per hour, along with aPTT control, with a disappearance of the symptoms after 72h.#Suspicion of OVT should be...