Fig 2. Results of PCR amplification of an- tibody gene fragments M. Phix 174 RF DNA/HaeIII; 1. Huκ chain; 2. Hu Vε ; 3. Nested PCR products (VH- BACK and HuIgGFOR used as primers in first round); 4. Nested PCR products (VHBACK and HuIgMFOR used as primers in first ...
Conclusion: Our results suggest that genetic variation within Myostatin may play a role in regulating the variation in fat mass in Chinese males. Additionally, the Myostatin gene may be a candidate that determines body fat mass in Chinese men. Keywords: Myostatin; single nucleotide polymorphism (...
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We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2), which is essential for kinetochore formation and promotes tumorigenesis in mammalian cells. However, the in vivo function of CUG2 has not been studied in animal models. Results To study the function of CUG2 in vivo, ...
Results: There was no change in calcium levels following 1,25 (0H)2 D3 in-take. Although baseline levels were similar,there was a significant de-cline in phosphorus concentrations after glucose administration on all occasions. The areas under the glucose and insulin curves during 0GTT are ...
For this figure, the NH2 tail of γENaC was overexpressed with a nuclear marker (DsRed2-N; noted with asterisk). These results clearly show that all three of the COOH termini of ENaC subunits co-localize with the membrane marker. Moreover, the NH2 terminus of αENaC, but not β and ...
results. The conditions for sample application suggested by the manufacturer were conducted. To identify candi- date oncogenic alleles, any changes that were also present in normal control samples were excluded. Definition of clinical endpoints Complete remission (CR) was defined as a normocel- lular...
We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2), which is essential for kinetochore formation and promotes tumorigenesis in mammalian cells. However, the in vivo function of CUG2 has not been studied in animal models. Results To study the function of CUG2 in vivo, ...
3a). These results indicated that the mutant mice exhibited abnormal retention of fear memory in an auditory cued test. In an open field test, mice were placed in a bright open-field apparatus (see Methods). While the total traveled distance was not significantly different between Math2-Cre;...
Results HFD induces Obesity and Type II Diabetes in Mice HFD mice had a significant increase in body weight relative to LFD and HFD-LFD at all time-points, (24 weeks- LFD: 33.75 g ± 2.27, HFD: 49.05 g ± 2.24; HFD-LFD: 28.8 g ± 7.03, p < 0.0001...