type 2 diabetes(T2D),and the place of fenofibrate was defined in the algorithm.The expert recommendations,and the algorithm provided in this review will serve as a guide to the clinicians to reconsider the adjunctive use of fenofibrate for preventing the progression of DR in selected T2D patients...
As far as we know, this is the first study that compares the antioxidant and anti-proliferative activities as well as the levels of the four bioactive compounds, in the major pomegranate tree organs and fruit sections. 2. Materials and methods 2.1. Plant materials The ‘Wonderful’ pomegranate...
In the final model, while also adjusting for relevant clinical features, only parafoveal vessel density in the DCP remained as a significant predictor of NPDR ETDRS level (OR = 0.54 (95% CI 0.32–0.92), = 0.024).Our results suggest that parafoveal vessel density in the DCP is the...
The primary endpoint is the progression of DR during follow-up, which is defined as an increase of two or more steps in the ETDRS scale. The secondary endpoints include the concomitant changes in visual acuity, presence, number, location and type of retinal lesions, and retinal blood vessel ...
Graviola (Annona muricata) is a small deciduous tree of the Annonaceae family, widely distributed in tropical countries (Figure 1A and Figure S1A,B), and commonly referred to as guanabana, soursop, or Brazilian paw-paw [28,29]. Graviola is an example of a natural plant source of anti-...
The long non-coding RNA X inactivate-specific transcript (lncRNA XIST) has been verified as an oncogenic gene in non-small cell lung cancer (NSCLC) whose regulatory role is largely unknown. The important tumor suppressors, microRNAs: miR-449a and miR-16
While mutations in protein coding genes undoubtedly initiate and promote PDAC, it is possible that noncoding RNAs (ncRNA) play a causative role as well. Numerous profiling and sequencing studies over the past decade have demonstrated that ncRNAs are differentially expressed in PDAC. We and others ...