More recent data has also shown that radiological diagnostics have good accuracy to assess for NASH specifically. In this chapter, we will highlight the current data in support of imaging protocols for noninvasive diagnosis of NASH and outline areas in need of further investigation in this realm....
Non-alcoholic fatty liver disease (NAFLD) is considered to be the hepatic manifestation of the metabolic syndrome and is characterized by ectopic accumulation of triglycerides in the cytoplasm of hepatocytes, i.e., steatosis. NAFLD has become the most common chronic liver disease, with an estimated...
that the noninvasive diagnostic methods for NAFLD still cannot be used as a substitute for LB, but a combination of serum cytokeratin 18 fragments, NAFLD fibrosis score, and FibroScan can make for primary diagnosis of NASH with or without advanced fibrosis, so as to decide the use of LB.BAI...
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of metabolic syndrome. Despite its prevalence and the importance of early diagnosis, there is a lack of robustly validated biomarkers for diagnosis, prognosis and monitori...
Accordingly, severalnon-invasive markers have been evaluated for thediagnosis of simple steatosis and NASH, including bothserological indices and imaging methods. The presentreview summarizes the current knowledge on the roleof these markers in the diagnosis of NAFLD. Currentdata suggest that ultrasound ...
This Review discusses the advantages and limitations of noninvasive methods for the management of adults with NAFLD, including diagnosis and quantification of steatosis, diagnosis of NASH and staging of hepatic fibrosis. 展开 关键词: NONALCOHOLIC FATTY LIVER CHRONIC HEPATITIS-C CONTROLLED ATTENUATION ...
Liver biopsy remains the gold standard for evaluating the degree of hepatic necroinflammation and f ibrosis; however, several noninvasive investigations, such as serum biomarkers, have been developed to establish the diagnosis and also to evaluate treatment response. These markers are currently neither...
The diagnosis of non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) is limited by the need for liver biopsy. We aimed at testing the accu... J Shen,LY Chan,LH Wong,... - 《Journal of Hepatology》 被引量: 373发表: 2012年 Non-invasive diagnosis of nonalcoholic fatty ...
NASH diagnosis NASH is currently diagnosed histologically and requires a liver biopsy. A liver biopsy is an invasive and subjective procedure that entails complications (the risk of death is close to 0.01%), and is prone to sampling errors. ...
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of metabolic syndrome. Despite its prevalence and the importance of early diagnosis, there is a lack of robustly validated biomarkers for diagnosis, prognosis and monitori...