In accordance with the Expert Panel Consensus statement, NAFLD (including non-alcoholic steatohepatitis (NASH)) was identified as ICD-10 K76.0, K75.8, and ICD-9 571.8. Hospital admissions data were available until September 30, 2021, for centers in England, July 31, 2021, for centers in ...
Background: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are highly prevalent but underdiagnosed. Aims: We used an electronic health record data network to test a population-level risk stratification strategy using noninvasive tests (NITs) of liver fibrosis. Methods...
NAFLD may progress in some instances to steatohepatitis, hepatic fibrosis, and cirrhosis9 and hepatic steatosis is frequently associated with other disorders, including cardiovascular disease10, diabetes11, chronic kidney disease12, and colorectal cancer13. Like OSA, NAFLD is closely related to obesity...
2 The disease encompasses the full spectrum of fatty liver disease, including nonalcoholic fatty liver, nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis.2,3 Although individuals with NAFLD are typically asymptomatic, NASH has been associated with increased risk of advanced fibrosis,...
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. J Hepatol. 2020;73(2):241–51. Article CAS PubMed PubMed Central Google Scholar Bycroft C, Freeman C, Petkova D, Band G, Elliott LT, Sharp K, et al. The UK Biobank ...
HBV and HCV cases. A. Overall survival of the three groups; B. Recurrence free survival for all three groups. The figure is adapted from Benhammouet al. from Bedside to Bench-side: the Clinical, Epidemiological and Molecular Basis for Nonalcoholic Steatohepatitis and Hepatocellular Carcinoma.UCLA...
The regulation of M1/M2 polarization in liver macrophages is closely associated with the progression of nonalcoholic steatohepatitis (NASH); however, the mechanism involved in this process remains unclear. Here, we describe the orphan nuclear receptor retinoic-acid-related orphan receptor α (RORα) ...
Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: Mechanisms, treatment and prevention. Ann. Transl. Med. 2021, 9, 729. [Google Scholar] [CrossRef] Sayiner, M.; Koenig, A.; Henry, L.; Younossi, Z.M. Epidemiology of Nonalcoholic Fatty...
Keywords: nonalcoholic fatty liver disease; NAFLD; nonalcoholic steatohepatitis; management; psoriasis 1. Introduction Psoriasis is a chronic, immune-mediated, inflammatory skin disease that affects approximately 2%–3% of the adults in the general population of Western countries [1,2]. This disease ...
Background:Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic fatty liver and non-alcoholic fatty steatohepatitis, is associated with increased incidence of heart failure (HF). Previous studies have shown an association of NAFLD with increased incidence of ventricular arrhythmias (VAs)....