Human single nucleotide polymorphisms (SNPs) represent the most frequent type of human population DNA variation. One of the main goals of SNP research is to understand the genetics of the human phenotype variation and especially the genetic basis of human complex diseases. Non-synonymous coding SNPs...
网络非同义单核苷酸多态性研究 网络释义 1. 非同义单核苷酸多态性研究 ...Consortium,TASC)进行的14500个非同义单核苷酸多态性研究(non-synonymous SNPs),还发现AS与ERAP-1和IL-23R两 … zh.wikipedia.org|基于26个网页
Evaluation of disease status by imputation of 41 diagnostic single nucleotide polymorphisms (SNPs) and a common haplotype published in 2013 identified several suspected carriers in the current breeding population, which suggests a higher frequency of the Weaver allele than anticipated. In order to ...
Over the past few years, severalin silicoapproaches have been developed particularly for screening functional SNPs and detecting the effect of deleterious nsSNPs in the candidate protein. Many tools can also predict the structural changes based on single amino acid substitution in the protein24,25. B...
The SNPs of the ADAMTS3 gene were examined using the NCBI database (http://www.ncbi.nlm.nih.gov/) and the Ensembl genome browser (http://asia.ensembl.org/Homo_sapiens/Gene/Summary). Figure1illustrates that a total of 70,876 SNPs have been identified in Homo sapiens, of which 848 are...
Human single nucleotide polymorphisms (SNPs) represent the most frequent type of human population DNA variation. One of the main goals of SNP research is to understand the genetics of the human phenotype variation and especially the genetic basis of human complex diseases. Non-synonymous coding SNPs...
Single nucleotide polymorphisms (SNPs) are an abundant form of genetic variation in the genome of every species and are useful for gene mapping and association studies. Of particular interest are non-synonymous SNPs, which may alter protein function and phenotype. We therefore examined bovine expresse...
LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures. Bioinformatics. 2009;25:1431-2.Ryan M, Diekhans M, Lien S, Liu Y... M Ryan,M Diekhans,S Lien,... - 《Bioinformatics》 被引量: 108发表: 2009年 LS-SNP/PDB Ryan M, Diekhans M, Lien S, Liu Y, ...
(Fig.1) were mapped inIL-10gene sequence. Out of 1800 SNPs, 91 are non-synonymous SNPs (nsSNPs) found in the coding region that may lead to missense or nonsense mutations, subsequently affecting the protein's structure and function. Our investigation accounted for the nsSNPs in the coding ...
The SNPs of the ADAMTS3 gene were examined using the NCBI database (http://www.ncbi.nlm.nih.gov/) and the Ensembl genome browser (http://asia.ensembl.org/Homo_sapiens/Gene/Summary). Figure1illustrates that a total of 70,876 SNPs have been identified in Homo sapiens, of which 848 are...