Evaluation of non-linear-mixed-effect modeling to reduce the sample sizes of pediatric trials in type 2 diabetes mellitusMixed-effects model repeated measuresNon-linear-mixed-effects modelsPediatric extrapolationPower comparisonType 2 diabetes mellitus...
This thesis provides evidence that better characterization of pre-clinical and clinical data can be accomplished using non-linear mixed effect modeling (NLMEM) and more effective experiments can be conducted using optimal design (OD)... II Charles - 《Department of Pharmaceutical Biosciences》 被引量...
Linear mixed-effects modeling approach to FMRI group analysis. Neuroimage 73: 176–190. Chen G, Saad ZS, Nath AR, Beauchamp MS, Cox RW (2012). FMRI group analysis combining effect estimates and their variances. Neuroimage 60: 747–765. Cieslik EC, Mueller VI, Eickhoff CR, Langner R, ...
Modeling of the time-dependent multi-skilled RCPSP considering learning effect: An evolutionary solution approach Purpose - The purpose of this paper is to propose a new mixed-integer formulation for the time-dependent multi-skilled resource-constrained project schedul... AH Hosseinian,V Baradaran,M...
A mixed linear and non-linear logic: Proofs, terms and models Intuitionistic linear logic regains the expressive power of intuitionistic logic through the ! ('of course') modality. Benton, Bierman, Hyland and de Paiva have given a term assignment system for ILL PN Benton - DBLP 被引量: 390...
Non-linear, non-monotonic effect of nano-scale roughness on particle deposition in absence of an energy barrier: Experiments and modeling Chao Jin, Tomasz Glawdel, Carolyn L. Ren & Monica B. Emelko Scientific Reports volume 5, Article number: 17747 (2016) Cite this article 3374 Accesses ...
(Fig.3inset). For example, we achieved ~2.3-fold better results for height (24.1% vs 56.6% PVE) and ~6.5-fold better results for systolic blood pressure (4.0% vs 25.9% PVE) with linear mixed models. These results indicate that much of the effect is distributed among a large number of...
The trend of microwave circuits has been toward highly integrated systems. Most design tools for circuits are based on the fundamental circuit theory using the S-matrix combined with the harmonic-balance method. Consequently, the electromagnetic effect is ignored or approximated at best. Therefore, th...
This study describes a dynamic non-linear mathematical approach for modeling the course of disease in acquired brain injury (ABI) patients. Data from a multicentric study were used to evaluate the reliability of the Michaelis–Menten (MM) model applied to well-known clinical variables that assess ...
In this paper, we presented a non-linear surgical risk calculator (NL-SRC) for mixed data from multiple surgical fields, in which the Gradient Boosting Decision Tree (GBDT) model is used to obtain accurate postoperative risk prediction by capturing the non-linear interactions between/among risk ...