OBJECTIVE: The purpose of this report is to describe the case of a 43-year-old male with asthma who was hospitalized for an exacerbation of non-cystic fibrosis bronchiectasis (NCFB), a chronic lung disease that is characterized by dilation of the airways, persistent cough, chronic sputum ...
Non-cystic fibrosis bronchiectasis (NCFB) is a chronic lung disease characterized by progressive and irreversible changes of the bronchial tree due to persistent inflammatory processes in the airways. Its pathophysiology is based on the permanent and abnormal dilation of the bronchi and bronchioles1. T...
A diverse microbiota exists within the airways of individuals with non-cystic fibrosis bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes within the microbiome correlate with future disease progression is not yet known. We assessed the microbial community structure ...
Bronchiectasis is a chronic debilitating condition with considerable phenotypic diversity. A vicious cycle of infection and inflammation exists in damaged airways with patients suffering from persistent cough, purulent sputum production, recurrent chest infections and general malaise. The associated burden of ...
Wilson R, Aksamit T, Aliberti S, De Soyza A, Elborn JS, Goeminne P, Hill AT, Menendez R, and Polverino E: Chal- lenges in managing Pseudomonas aeruginosa in non-cystic fibrosis bronchiectasis. Respir Med. 2016;117:179-189.Wilson, R.; Aksamit, T.; Aliberti, S.; De Soyza, A.; ...
BronchiectasisCystic fibrosisNon-CF bronchiectasisImmunodeficiencyDiagnostic techniques and proceduresIn bronchiectasis a vicious circle of small airway dilatation, impairment of local defence mechanisms, infection and endobronchial inflammation cause irreversible lung destruction with progressive deterioration of ...
Once bronchiectasis has been confirmed it is vital that patients undergo further investigation to determine the underlying cause. The wide range of possible diseases requires a structured diagnostic approach. This paper reviews different causes of non-CF bronchiectasis (NCFB) and presents a diagnostic ...
Joish VN, Spilsbury-Cantalupo M, Operschall E, Luong B, Boklage S. Economic burden of non-cystic fibrosis bronchiectasis in the first year after diagnosis from a US health plan perspective. Appl Health Econ Health Policy 2013; 11:299-304....
Joish VN, Spilsbury-Cantalupo M, Operschall E, Luong B, Boklage S. Economic burden of non-cystic fibrosis bronchiectasis in the first year after diagnosis from a US health plan perspective. Appl Health Econ Health Policy 2013; 11:299-304....
No quantitative systematic review was found to report the efficiency and safety of surgical resection in the management of non-cystic fibrosis (non-CF) bronchiectasis. We therefore conducted a meta-analysis to assess the effects of operative intervention to patients with non-CF bronchiectasis. PubMed...