Note that the Gail model has been shown to accuratelyestimate the proportion of women (without a strong family history) who will develop cancer in largegroups but is a poor discriminator of risk among individuals. (2)Policy Number
Compared with the overall female population, the SIRs of female breast cancer patients with uterine (SIR: 2.66, 95% CI: 2.37–2.98), thyroid (SIR: 2.30, 95% CI: 2.02–2.62), and bone and soft tissue (SIR: 2.16, 95% CI: 1.56–2.91) cancers were significantly increased. Male breast ...
Mutations in the BRCA1 and BRCA2 genes are responsible for only a part of hereditary breast cancer (HBC). The origins of "non-BRCA" HBC in families may be attributed in part to rare mutations in genes conferring moderate risk, such as CHEK2, which encodes for an upstream regulator of BR...
Despite intense efforts to find additional high-risk breast cancer genes (BRCAx) using linkage analysis, none have been reported thus far. Here we explore the hypothesis that BRCAx breast tumors from genetically related patients share a somatic genetic etiology that might be revealed by array ...
Purpose: This systematic literature review summarizes clinical studies and trials involving combined non-ablative hyperthermia and re-irradiation in locoregionally recurrent cancer except breast cancer. Methods: One database and one registry, MEDLINE and
Noninvasive breast cancer includes ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS). Phyllodes tumors are rare stromal tumors whose histology and behavior vary from benign to malignant. In both DCIS and LCIS, abnormal cells are present within the lining of the duct or lobule ...
Harris. What is the optimal technique of irradiation in breast -conserving treatment? Non-Disseminated breast cancer. Controversial issues and management. Edited by Gilbert H. Fletcher and Seymour H.Levitt. Springler-Verlag 1993.Rutqvist L-E. Non-disseminated breast cancer. In: Fletcher G , ...
摘要: Background Mutations in the BRCA1 and BRCA2 genes are responsible for only a part of hereditary breast cancer (HBC). The origins of "non- BRCA" HBC in families may be attributed in part to rare...关键词: Biological Sciences(General Oncology Medicine(General ...
Davis Institute, Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, Quebec, Canada BACKGROUND: Recent data show that mutations in RAD51D have an aetiological role in ovarian carcinoma, yet mutations do not appear to be associated with an increased risk for breast cancer. ...
Background: Discrepancies may exist between what oncologists communicate and what patients understand about their cancer stage and its implications. Objective: We explored patients' ability to identify their stage of breast cancer. Methods: As part of a study testing a cancer self-management interventi...