Non-alcoholic fatty liver disease (NAFLD)--Pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. Drug Metab. Rev. 2017, 49, 197-211. [CrossRef] [PubMed]Cobbina, E. & Akhlaghi, F. Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and...
非酒精性脂肪肝(Nonalcoholic Fatty Liver Disease,NAFLD)是指酒精和其它明确的损肝因素之外所致的肝细胞内脂肪过度沉积引发的代谢应激性肝脏损伤。非酒精性脂肪性肝炎(Nonalcoholic Steatohepatitis,NASH)是NAFLD进展而来的严重慢性肝脏疾病,流行病学数据显示,15%～25%的NAFLD患者最终会发展为NASH。 全球平均每3个人中就...
NAFLD是指除外酒精和其他明确的损肝因素所致的肝细胞内脂肪过度沉积为主要特征的临床病理综合征,与胰岛素抵抗和遗传易感性密切相关的获得性代谢应激性肝损伤。包括单纯性脂肪肝(SFL)、非酒精性脂肪性肝炎(NASH)及其相关肝硬化。非酒精性脂肪性肝病除可直接导致失代偿期肝硬化、肝细胞癌和移植肝复发外,还可影响其他慢性...
Non-alcoholic fatty liver disease (NAFLD) is associated with low level of physical activity: a population-based study BACKGROUND: High intensity exercise improves metabolic status and may potentially mobilise hepatic fat. AIM: To assess the level of physical activity (PA) ... L Gerber,M Otgon...
非酒精性脂肪性肝病(Nonalcoholic Fatty Liver Disease,NAFLD)是一种与胰岛素抵抗和遗传易感密切相关的代谢应激性肝脏损伤,疾 病谱包括非酒精性肝脂肪变(NAFL)、非酒精性脂肪性肝炎(NASH)及NASH相关肝硬化和肝细胞癌。 NASH表现为5%以上的肝细胞脂 肪变合并小叶内炎症和肝细胞气球样变性,大约有15%~25%的NAFLD会...
Nonalcoholic fatty liver disease (NAFLD) is defined by fat deposition in the liver in the absence of alcohol abuse or other known hepatotoxins. It is a spectrum that includes nonalcoholic fatty liver (NAFL; fat deposition in the liver without inflammation) and nonalcoholic steatohepatitis (NASH;...
Fatty Liver Disease Types There are two main types of FLD: 1. Metabolic dysfunction-associated steatotic liver disease (MASLD) This type used to be called nonalcoholic fatty liver disease (NAFLD). It is very common in the U.S., affecting 1 in 3 adults. Researchers aren't exactly sure wh...
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in childhood. There is an increase in disease prevalence and diagnoses as it is difficult to diagnose the problem. There are currently no effective medications. Management of NAFLD is a challenge for primary care ...
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public health. NAFLD is the most common chronic liver disease in the Western world. NAFLD is closely associated with metabolic...
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disease1,2, and also an emerging risk factor for type 2 diabetes mellitus, cardiovascular disease, renal diseases and all-cause mortality3. The prevalence of NAFLD is reported to be approximately 25% worldwide4,...