exponentially falls to zero. Both, \(k_{\Lambda }\) and \(k_{\lambda },\) in general vary in time as a result of the transport, as indicated in Fig. 2. Evaluated at a fixed reference time \(t_{{\textrm{ref}}},\) the fixed-point solution (3) further defines the universal ...
If the number of non-zero values (white pixels) inside the window is greater than 5, then it is considered that both object and background are present in the window. Then at the same window on the original image at the corresponding edge pixel is binarized using Otsu’s thresholding. ...
For our analyses, we included genes whose non-zero mean levels were above 20.6 ncounts, corresponding to two copies per cell. Furthermore, we omitted genes that were detected in fewer than three cells unless there was evidence of expression in our bulk RNA-seq data. Using these methods, we...
The zero-sum game of pathway optimization: emerging paradigms for tuning gene expression. Biotechnol. J. 6, 1064–1070 (2011). Article CAS PubMed Google Scholar Jantama, K. et al. Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C ...
(right). By reducing the current amplitude in one electrode pair and increasing it in the second while keeping the current sum fixed, the stimulation locus can be steered toward the electrode pair with the smaller current amplitude14. Computation of TI stimulation locus in a human anatomical ...
Normalized FCS files were further loaded onto a Unix-based custom R script and all zero values were randomized into values between 0 to −1 using uniform distribution. Highly Multiplexed Combinatorial pMHC tetramer strategy Large-scale production of HLA monomer and pMHC library The inclusion bodies...
High-throughput transcriptome sequencing (RNA-seq) technology promises to discover novel protein-coding and non-coding transcripts, particularly the identification of long non-coding RNAs (lncRNAs) from de novo sequencing data. This requires tools that a
Unraveling functional noncoding variants associated with complex diseases is still a great challenge. We present a novel algorithm, Prioritization And Functional Assessment (PAFA), that prioritizes and assesses the functionality of genetic variants by in
wherey¯is the baseline value, ASD and TSC are binary group variables indicating the presence or absence of ASD and TSC, respectively, and age is the subject's age in years. The two-way ANCOVA then allows us to assess whetherβASDand/orβTSCis significantly different from zero, indicating...
The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Reprints and permissions About this article Cite this article Wang, Z., Zhu, T., Ma, W. et al. Genome-wide ...