There have been several successful applications of vGWAS in quantitative traits using either GWAS18,19,22 or gene expression data17,23,24. For example, Brown et al.17 reported abundant vGWAS signals within the major his- tocompatibility complex (MHC) region using RNA sequence data from ...
Accordingly, the multivariate statistical modeling with primary metabolites suggested a putative biomarker panel unique to the disease, and the dysfunctional metabolic traits were mainly characterized by the hyperactivity of the central carbon/nitrogen metabolisms. Furthermore, the metabolic discrepancy was ...
Existing research suggests that the difference in muscular traits between these two breeds is due to gene mutations [23,24] and the influence of microRNAs [25]. However, information about skeletal muscle development-related lncRNAs in sheep is limited. Building on previous studies, we thus ...
4.1. Persistence of Maternal Exposure to Adverse Environmental Conditions along Generations In some cases, developmentally programmed traits may simply be the result of persistent or replicated exposure during critical periods of development, generation after generation. It has been suggested that the ...