The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer. Oncotarget. 2017;8:5233. Article PubMed Google Scholar Wang Z, Ren B, Huang J, Yin R, et al. LncRNA DUXAP10 modulates cell proliferation in ...
Most lung cancer instances are non-small cell lung cancers (NSCLC). As stated by recent literature, cycloxygenase-2 (COX-2) is upregulated in lung adenocarcinomas. COX-2 relates to enhanced cell proliferation and reduced apoptosis; both of which are essential for an invasive tumor growth and ...
E. et al. Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up †. (2017). https://doi.org/10.1093/annonc/mdx222 Schneider, B. J. et al. Lung cancer surveillance after definitive curative-intent therapy: ...
Most cancer deaths are caused by metastasis: recurrence of disease by disseminated tumour cells at sites distant from the primary tumour. Large numbers of disseminated tumour cells are released from the primary tumour, even during the early stages of tum
Lymphoplasmacytic lymphoma (LPL) is one type of low-grade small B-cell lymphoproliferative disorder, often with a spectrum of small lymphocytes, plasmacytoid lymphocytes, and plasma cells. Most LPL cases are associated with an immunoglobulin M (IgM) paraprotein, and involving bone marrow, clinically...
Integration of multiple "OMIC" biomarkers: a precision medicine strategy for lung cancer Lung Cancer, 107 (2017), pp. 50-58 Google Scholar [12] J.K. Nicholson, J.C. Lindon, E. Holmes ’MEtabonomics’: understanding the metabolic responses of living systems to pathophysiological stimuli via mu...
Zhang X, Yang D, Wei Y (2018) Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer. Onco Targets Ther 11:3979–3987. https://doi.org/10.2147/OTT.S158316 Article PubMed PubMed Central Google Scholar Zhang R, Xu J, Zha...
Inflammation is an essential pillar of the immune defense. On the other hand, chronic inflammation is considered a hallmark of cancer initiation and progre
1e). In addition, various pathways that we had previously found to be differentially enriched in cultured hand and knee SF in vitro17, were also joint-specifically activated in vivo, such as cell adhesion, extracellular matrix (ECM) interaction and bone remodeling/osteoclast differentiation pathways...
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early assessment of chronic disorders encompass acute phase proteins (APP), cytokin