The prevalence of non-small-cell lung cancer (NSCLC) is rising every year all around the world. The interaction between cancer cells and the tumor microenvironment (TME) is a crucial factor in determining the development of human neoplasms. Organellar and cellular stress are induced during ...
Screening of an oncolytic virus and its anti-tumor effects in multiple tumor models.aNon-small cell lung cancer cells (NSCLCs; A549, NCI-H1299, NCI-H460), hepatocarcinoma cells (Hep3B, HepG2, PLC/PRF/5), cervical carcinoma cells (HeLa) were infected with CV-B3/Nancy, CV-B5/Faulkner ...
This study compared the survival outcomes after thermal ablation versus wedge resection in patients with stage I non-small cell lung cancer (NSCLC) ≤ 2 cm. Data from the United States (US) National Cancer Institute Surveillance Epidemiology a
Association of Broad-Based Genomic Sequencing With Survival Among Patients With Advanced Non–Small Cell Lung Cancer in the Community Oncology Setting Carolyn J. Presley, MD1; Daiwei Tang, BS2; Pamela R. Soulos, MPH3; et al Anne C. Chiang, MD, PhD3; Janina A. Longtine, MD3; Kerin B....
The efficacy of checkpoint inhibitor (CPI) immunotherapy in patients with non–small cell lung cancer (NSCLC) is limited by a lack of strongly predictive response markers, subjecting patients to potential underutilization of alternative effective treatments, increased risk for futile care, and unnecessar...
Figure 4. Distribution of Initial Treatment by NSCLC Stage (SEER-18, 2016) View LargeDownload NSCLC indicates non–small cell lung cancer; SEER-18, Surveillance, Epidemiology, and End Results. A, for all ages; B, for those younger than 65 years; and C, those aged 65 years or older. Mu...
The objective of this project was to assess the best measure for postoperative outcomes by comparing 30-day and 90-day mortality rates after surgery for non–small cell lung cancer using the National Cancer Database. Secondarily, hospital performance was examined at multiple postoperative intervals to...
We used the main diagnosis to define our primary outcomes; the ICD9 and ICD10 version codes 410–414 and I20-I25 defined IHD (including angina pectoris, myocardial infarction, and other ischemic heart diseases). The validity, in terms of specificity, of primary diagnoses of MI in the ...
Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. N Engl J Med. 2018;378(2):113-125. doi:10.1056/NEJMoa1713137PubMedGoogle ScholarCrossref 10. Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-...
Betapudi, Venkaiah, et al., “Distinct Roles of Nonmuscle Myosin II Isoforms in the Regulation of MDA-MB-231 Breast Cancer Cell Spreading and Migration”, Cancer Res 2006; 66: (9). May 1, 2006, (May 1, 2006), 4725-4733. Betapudi, Venkaiah, et al., “Life without double-headed...